Results 221 to 230 of about 322,888 (285)

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Comment on Rose et al.: the need for responsible collection and reporting of demographic data in drug checking research. [PDF]

Harm Reduct J
Airth L, Goodyear T.
europepmc   +1 more source

Nigra‐Subthalamic Dopaminergic Circuitry Modulates and Represents Distinct Pain Modality in Physiological and Pain States in Mice

Advanced Science, EarlyView.
Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji, Shuyi Li, Jiaqi Zhang, Xiang‐Ying Xu, Cui Yin, Mu Niu, Danyang Liu, Yanyu Jiang, Yong Niu, Su Liu, Bin Zhang, Guiyun Cui, Chunyi Zhou, Cheng Xiao   +13 more
wiley   +1 more source

Planning and implementing community-based drug checking services in Scotland: a qualitative exploration using the consolidated framework for implementation research. [PDF]

Subst Abuse Treat Prev Policy
Falzon D, Carver H, Masterton W, Wallace B, Sumnall H, Measham F, Craik V, Gittins R, Aston EV, Watson K, Hunter C, Priyadarshi S, Parkes T.   +12 more
europepmc   +1 more source

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What is drug checking, anyway?

Drugs, Habits and Social Policy, 2022
Purpose The recent influx of interest in and the changing status of drug checking has led us to reconsider some fundamental questions about drug checking. This commentary aims to define drug checking. It proceeds in three parts: terminology, definitions and programmes that are excluded from the definition of drug checking that still have value for ...
Monica J. Barratt, Fiona Measham
openaire   +3 more sources

Integriertes Drug-Checking

PiD - Psychotherapie im Dialog, 2023
Drug-Checking ist eine Maßnahme zur Schadensminderung für sozial integrierte Konsumierende in Partysettings. Dabei können illegale Substanzen auf ihre Inhaltsstoffe und schädliche Beimengungen untersucht werden. Integriertes Drug-Checking beinhaltet zudem Beratung zu akuten und langfristigen Risiken des Konsums.
Karsten Tögel-Lins, Bernd Werse, Heino Stöver   +2 more
openaire   +1 more source

Drug checking identifies counterfeit alprazolam tablets

Drug and Alcohol Dependence, 2021
Non-prescribed benzodiazepine use is increasing in North America, especially among youth. Owing to increasing demand, counterfeit benzodiazepine tablets are mass-produced in clandestine, unregulated environments and sold as legitimate pharmaceuticals.
Samuel Tobias, Aaron M. Shapiro, Cameron J. Grant, Priya Patel, Mark Lysyshyn, Lianping Ti   +5 more
openaire   +2 more sources

Xylazine Test Strips for Drug Checking

Canadian Journal of Health Technologies, 2023
Why is this an issue? The opioid crisis is an ongoing public health concern in Canada. In 2022, a total of 7,328 apparent opioid toxicity deaths were reported, which is an average of 20 deaths per day. Xylazine, referred to as tranq, is an animal tranquilizer that has appeared as an adulterant in the unregulated drug supply ...
Sarah Jones, Sharon Bailey
openaire   +1 more source

Drug checking in New Zealand: the 2020 and 2021 drug and substance checking legislation acts

Drugs, Habits and Social Policy, 2022
Purpose This paper aims to explore the context and implications of the New Zealand Drug and Substance Drug Checking Acts 2020 and 2021. Design/methodology/approach This discussion provides a description of legislative changes about drug checking in the New Zealand context, alongside a critical analysis of the interlinked factors surrounding these ...
openaire   +1 more source