Results 201 to 210 of about 6,210,399 (255)

The Detection of Novel Nitazene-Class Opioids in Unregulated Drug Markets in Canada. [PDF]

Drug Alcohol Rev
Gelgoot EA, Scarfone KM, Maghsoudi N, McDonald K, Hao W, Stefan C, Beriault DR, Delaney SR, Ti L, Tobias S, Bowles JM, Werb D, Members of Toronto's Drug Checking Service.   +12 more
europepmc   +1 more source

Copula‐based joint modelling of emergency department visits with time‐varying dependence

Canadian Journal of Statistics, EarlyView.
Abstract Jointly modelling multiple correlated count time series is essential in health services research, where outcomes like emergency visits for mental health and substance use often evolve together. Ignoring these dependencies can obscure meaningful trends and limit the effectiveness of policy evaluation.
Guanjie Lyu, Cindy Feng, Lihui Liu
wiley   +1 more source

Purification, Fluorescent Labeling, and Detyrosination of Mammalian Cell Tubulin for Biochemical Assays

Cytoskeleton, EarlyView.
ABSTRACT Microtubules play essential roles in numerous cellular processes. All microtubules are built from the protein tubulin, yet individual microtubules can differ spatially and temporally due to their tubulin isotype composition and post‐translational modifications (PTMs).
Ezekiel C. Thomas, Yang Yue, Morgan L. Pimm, Takashi Hotta, Ryoma Ohi, Kristen J. Verhey   +5 more
wiley   +1 more source

Medetomidine Exposure in a Shifting Drug Landscape: Insights From Patient Experiences. [PDF]

Ann Intern Med
Pressimone C, Alfaro L, Hull I, Jawa R, Roy P, Liebschutz J, Shang M.   +6 more
europepmc   +1 more source

Investigating the Cytoskeleton of DRGs Using Cryo‐Electron Microscopy and Deep Learning

Cytoskeleton, EarlyView.
ABSTRACT We describe a method for determining the ultrastructural organization of axons and varicosities of cultured dorsal root ganglion (DRG) neurons using cryogenic electron microscopy (cryo‐EM). Cryo‐EM reveals the dimensions, proximity, and overall organization of biological specimens in a near‐native state, avoiding artifacts of fixation and ...
M. Neal Waxham, Mihir Relan, Matthew T. Swulius, Andrea K. H. Stavoe   +3 more
wiley   +1 more source

Living with addiction in the shadow of punishment: a qualitative study of prison drug use and harm reduction in Iceland. [PDF]

Int J Circumpolar Health
Yeoman MD, Fridjónsdóttir HS, Klinke ME.   +2 more
europepmc   +1 more source

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

Cytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith, Lauren A. Tauer, Randall H. Friedline, Xiaodi Hu, Duy Tran, Yangyi E. Luo, Nacima Hadjout‐Rabi, Elisabeth R. Barton, Jason K. Kim, Elizabeth J. Luna   +9 more
wiley   +1 more source

Interpol review of forensic drug chemistry, 2022-2025. [PDF]

Forensic Sci Int Synerg
Love D, Page E.
europepmc   +1 more source

Motor Physiology Transcranial Magnetic Stimulation–Based Biomarkers and Associated Neurocognitive Profiles in Attention‐Deficit/Hyperactivity Disorder

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Purpose Attention‐deficit/hyperactivity disorder (ADHD) is a highly prevalent and heterogeneous neurodevelopmental condition for which current diagnostic approaches rely on symptom‐based classifications that do not capture underlying neurobiology.
Alyssa C. DeRonda, Alice Sperry, Deana Crocetti, Karlee Migneault, Paul S. Horn, Donald L. Gilbert, Keri S. Rosch, Stewart H. Mostofsky   +7 more
wiley   +1 more source

Global emergence and γ-aminobutyric acid type A (GABA_A) receptor activity of the new designer benzodiazepine ethylbromazolam. [PDF]

Arch Toxicol
Norman C, Acreman D, Bissram M, Curtis B, Hamer S, Westphal F, Putz M, Stefan C, Delaney SR, Lines R, McLeod MD, McDonald K, Green H.   +12 more
europepmc   +1 more source