Results 41 to 50 of about 6,210,399 (255)

City checking: Piloting the UK's first community‐based drug safety testing (drug checking) service in 2 city centres [PDF]

British Journal of Clinical Pharmacology, 2020
AimsTo explore the feasibility of delivering community‐based drug safety testing (drug checking), to trial service design characteristics and to compare with festival‐based testing.MethodsIn total, 171 substances of concern were submitted on 5 dates at 3 venues in 2 UK cities and tested using up to 6 analytical techniques.
openaire   +2 more sources

Drug sellers' use of a drug checking service amid the overdose crisis in British Columbia, Canada. [PDF]

Addiction
Abstract Aims This study examined the use of a drug checking service by drug sellers in British Columbia, Canada, to assess motivations for service use and substances intended for distribution, focusing on risks associated with an unstable illicit drug market.
Gonzalez-Nieto P, Wallace B, Kielty C, Shkolnikov I, Margolese A, Arredondo Sanchez Lira J, Gill C, Hore D.   +7 more
europepmc   +4 more sources

“We're gonna want to know the label's right”: Co-designing a drug checking service for anabolic-androgenic steroid consumers

, 2023
Introduction: Of the current harm reduction initiatives available drug checking is presently surrounded by the most contention in Australia. Drug checking is an integrated service allowing consumers to have their substances analysed and receive harm ...
Kill, Emma, Puljevic, Cheneal, Ferris, Jason, Dunn, Matthew, Piatkowski, Timothy, Francis, Cameron   +5 more
core   +1 more source

Identification of isotocyanozene at an Australian drug checking service

Forensic Chemistry
Novel synthetic opioids of the 'nitazene' class, comprised of 2-benzylbenzimidazole opioids and related derivatives, present a growing threat to public health. Most recently emerging in European drug markets in 2019, the nitazene group of drugs has been associated internationally with adverse effects in drug users, overdose clusters, and significant ...
Curtis, Blake, Lawes, Douglas J., Persson, Mattias, Caldicott, David, Green, Henrik, Norman, Caitlyn, McLeod, Malcolm D.   +6 more
openaire   +2 more sources

A systematized review of drug-checking and related considerations for implementation as a harm reduction intervention.

, 2023
Drug-checking services (DCS) provide people who use drugs (PWUD) the opportunity to have their substances tested before consumption. Though some suggest they may have adverse consequences, DCS have been introduced as a harm reduction (HR) strategy.
Ivers, Jo-Hanna, Keenan, Eamon, Killeen, Nicki, Giulini, Francesca   +3 more
core   +1 more source

Feasibility study of using mobile phone-based experience sampling to assess drug checking by opioid street drug users

Pilot and Feasibility Studies, 2023
Background To date, evaluations of take-home fentanyl (and/or benzodiazepine) test strip use — the most common form of drug checking services — and potential effects on overdose risk have relied on retrospective accounts for some preceding time period ...
James A. Swartz, Mary Ellen Mackesy-Amiti, A. David Jimenez, Lisa Robison-Taylor, Elizabeth Prete   +4 more
doaj   +1 more source

“They sent it away for testing and it was all bunk”: Exploring perspectives on drug checking among steroid consumers in Queensland, Australia

, 2023
Introduction: Research supports the feasibility and acceptance of drug checking among nightlife and festival attendees. Interest in expanding drug checking to other groups of people who use drugs, including those who inject drugs, has grown.
Cheneal Puljevic, Jason Ferris, Puljevic, Cheneal, Ferris, Jason, Cameron Francis, Timothy Piatkowski, Matthew Dunn, Dunn, Matthew, Piatkowski, Timothy, Francis, Cameron   +9 more
core   +1 more source

Drug checking to detect fentanyl and new psychoactive substances [PDF]

, 2020
Purpose of reviewDrug checking services invite drug consumers to anonymously submit drug samples for chemical analysis and provide feedback of results. Drugs are tested for strength/dose and/or presence of adulterants.
Palamar, JJ, Salomone, A, Barratt, MJ ; https://orcid.org/   +2 more
core   +1 more source

Who uses drug checking services? Assessing uptake and outcomes at English festivals in 2018. [PDF]

, 2022
Purpose: This study aims to assess service user characteristics, uptake and outcomes for drug checking services offered to over 250,000 English festival-goers in summer 2018 and to compare findings with earlier years, wider festival-goers and the general
Measham, Fiona, Simmons, H, Simmons, Henry, Measham, F   +3 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source