Prevalence of psychoactive substances in Dutch and Belgian traffic [PDF]
, 2012 Objective: The purpose of this study was to compare the prevalence of psychoactive substances in general traffic in The Netherlands and Belgium. Method: Randomly selected car drivers and drivers of small vans in six police regions in The Netherlands and ...
Brookhuis, Karel +5 more
core +7 more sources
An implantable microdevice to perform high-throughput in vivo drug sensitivity testing in tumors [PDF]
, 2014 Current anticancer chemotherapy relies on a limited set of in vitro or indirect prognostic markers of tumor response to available drugs. A more accurate analysis of drug sensitivity would involve studying tumor response in vivo.
Baselga, Jose +7 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser +5 more
wiley +1 more source
Atomic Force Microscopy-Based Screening of Drug-Excipient Miscibility and Stability of Solid Dispersions [PDF]
, 2018 : Purpose: Development of a method to assess the drug/polymer miscibility and stability of solid dispersions using a melt-based mixing method. Methods: Amorphous fractured films are prepared and characterized with Raman Microscopy in combination with ...
Alsenz, Jochem +8 more
core
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li +9 more
wiley +1 more source
In silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma. [PDF]
, 2016 The long-term overall survival of Ewing sarcoma (EWS) patients remains poor; less than 30% of patients with metastatic or recurrent disease survive despite aggressive combinations of chemotherapy, radiation and surgery.
Alturkmani, Hani +11 more
core +3 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Publisher Correction: Network-based prediction of drug combinations
Nature Communications, 2019 The original version of this Article contained an error in Acknowledgements, which incorrectly omitted the following: ‘This work was also supported by NHLBI grant P01HL132825 to A.-L.B.’ This has been corrected in both the PDF and HTML versions of the ...
Feixiong Cheng +2 more
doaj +1 more source
Predicting Adverse Drug Reactions of Two-drug Combinations using Structural and Transcriptomic Drug Representations to Train a Artificial Neural Network [PDF]
, 2020 Susmitha Shankar +4 more
openalex +1 more source
Supplementary File 7 from Identification of Optimal Drug Combinations Targeting Cellular Networks: Integrating Phospho-Proteomics and Computational Network Analysis [PDF]
, 2023 Sergio Iadevaia +4 more
openalex +1 more source