Results 61 to 70 of about 27,194 (296)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Регуляторные исследования и экспертиза лекарственных средствINTRODUCTION. The Russian Federation has decided to restore the system of compounding pharmacies as an element of the critical national healthcare infrastructure and pharmaceutical supply chain.
S. E. Erdni-Garyaev +6 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Drug Compounding: FDA Authority and Possible Issues for Congress [PDF]
, 2018 This report discusses legislation regulating the compounding of drugs by pharmacies to remove certain ingredients from a standard approved drug for patients with allergies, or for a medical clinic to keep on hand.
Dabrowska, Agata
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Navigating the Path to Safe Compounding in Health Systems
, 2023 Across the country health systems are facing increasing drug shortages that are forcing pharmacists to rely far more heavily on compounding to meet the needs of patients.
Kimble, Craig +2 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Enhanced 2D Hand Pose Estimation for Gloved Medical Applications: A Preliminary Model
Sensors(1) Background: As digital health technology evolves, the role of accurate medical-gloved hand tracking is becoming more important for the assessment and training of practitioners to reduce procedural errors in clinical settings.
Adam W. Kiefer +4 more
doaj +1 more source
Contamination identified in additional medical products from New England Compounding Center [PDF]
November 1, 2012, 18:00 ET (6:00 PM ET)CDC HAN-00333-2012-11 -01-ADV-NSummary: As part of the ongoing investigation of the multistate outbreak of fungal meningitis and other infections, the Centers for Disease Control and Prevention (CDC) and the Food ...
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Consensual classification of drug and nondrug compounds
International Journal of Computational Biology and Drug Design, 2008 A special consensual approach is discussed for separating a molecular group with a proven pharmacological activity from another molecular group without any activity. It is mainly a group decision to produce a consensus of multiple classification results obtained with a single classification algorithm.
Pehlivanlı, Ayça C. +2 more
openaire +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source