Results 71 to 80 of about 27,194 (296)

OPINION AND EXPECTATION OF PHARMACISTS ON PROVIDING EXTEMPORANEOUS COMPOUNDING IN JOGJAKARTA AND CENTRAL JAVA PROVINCES, INDONESIA

open access: yes, 2017
Objective: This study was conducted to identify opinion and expectations of pharmacists on providing extemporaneous drug compounding to support pharmacy service. Methods: The study was conducted in Indonesia. Twenty pharmacists, age 40 and above, working
Niken Nur Widyakusuma   +3 more
core   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Pharmacy Compounding after the Drug Quality and Security Act

open access: yes, 2014
On November 27, 2013, President Obama signed into law the Drug Quality and Security Act ( DQSA ), which amends the Federal Food, Drug, and Cosmetic Act ( FDCA ) to add statutory provisions addressing drug compounding and supply chain issues. This article
Lietzan, Erika
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Federal Authority to Regulate the Compounding of Human Drugs [PDF]

open access: yes, 2013
This report will examine the FDA's regulation of drug compounding and will discuss relevant legal authorities. The report will conclude by discussing potential limits to the FDA's authority to regulate human drug ...
Nolan, Andrew
core  

Challenge of paediatric compounding to solid dosage forms sachets and hard capsules - Finnish perspective [PDF]

open access: yes, 2017
Objectives The study evaluated the quality of compounded sachets and hard gelatine capsules and their feasibility in paediatric drug administration.
Pellinen, Jukka   +8 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Nationwide voluntary recall of all products for sterile use from compounding pharmacy located in Cedar Park, Texas [PDF]

open access: yes
August 14, 2013, 16:00:00 ET (4:00:00 PM ETCDCHAN-00353Summary: The U.S. Food and Drug Administration (FDA) is alerting health care providers and patients of a voluntary nationwide recall of all products produced and distributed for sterile use by ...

core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The Influence of Tablet Formulation, Drug Concentration, and pH Modification on the Stability of Extemporaneously Compounded Levothyroxine Suspensions.

open access: yes, 2018
Three brands of levothyroxine tablets are currently available in New Zealand (Eltroxin, Mercury Pharma, Synthroid) for extemporaneous compounding into suspensions.
Lin, S-W   +10 more
core  

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