Results 101 to 110 of about 2,428,128 (309)

N-nitrosamine risk assessment in pharmaceuticals: Where are we from a regulatory point of view in 2025?

open access: yesJournal of Pharmaceutical and Biomedical Analysis Open
N-nitrosamines have been a concern for decades due to their potential mutagenicity and widespread occurrence across various matrices. While evidence suggests carcinogenicity in animals, their potential carcinogenicity in humans has prompted their initial
Yue Zhang   +4 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Investigation of Ingavirin® Antiviral Activity Against Season Influenza Virus A/H1N1 in MDCK Cell Culture

open access: yesАнтибиотики и Химиотерапия, 2020
Ingavirin® is low toxic for the MDCK cell culture. The drug concentration of 1000 mcg/ml does not reach the CD50 value. The antiviral activity of Ingavirin® was studied with respect to the influenza virus A/H1N1, including the Remantadin® resistant ...
G. A. Galegov   +2 more
doaj  

Strategies for Abatement of Contamination of Tableted Live Plague Vaccine at Different Stages of Manufacturing

open access: yesПроблемы особо опасных инфекций, 2016
Nowadays, problem of tableted drug form contamination with extraneous micro-flora is in the spotlight of scientists, as the specific share of these medical preparations in the world market amounts to more than 60 % and has a tendency to increase.
A. S. Tumanov   +11 more
doaj   +1 more source

Ana Liffey Drug Project annual report 1993

open access: yes, 1994
I note that the Project commenced in 1982 and since that time the range and level of services has been developed significantly. The Project was established at a time when the need for services for people with HIV/AIDS had not become apparent and it ...
Ana Liffey Drug Project
core  

Perspectives on drugs: Drug consumption rooms: an overview of provision and evidence. [PDF]

open access: yes, 2016
Supervised drug consumption facilities, where illicit drugs can be used under the supervision of trained staff, have been operating in Europe for the last three decades.

core  

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Perspectives on drugs: Internet-based drug treatment. [PDF]

open access: yes, 2014
The Internet is now recognised as a plausible vehicle for delivering drug and alcohol education, prevention and treatment programmes in a range of settings.

core  

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