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Ohio BWC Drug-Free EZ Program : technical assistance manual : reference/resource guide

open access: yes, 2002
Title from title screen (viewed Sept. 24, 2004).; "BWC-7648 (Rev. 7/18/2002)"--Screen 87 (i.e. p. 1 of form: Progress report, Drug-Free Workplace/Drug-Free EZ Program).; Electronic text (pdf, 89 p.).; Harvested from the web on 9/24 ...
Drug-Free EZ Program (Ohio. Bureau of Workers' Compensation)
core  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Cocaine contamination in pubic hair: Analysis of the decontamination method

open access: yesEgyptian Journal of Forensic Sciences, 2014
Even if pubic hair represents a reliable and widely accepted alternative hair matrix to identify drug abusers, it might produce false positive results due to external contamination.
Guido Romano   +4 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Compounding drugs contaminated with fungi: a recipe for disaster

open access: yesEmerging Microbes & Infections, 2012
Emerging Microbes & Infections (2012) 1, e41; doi:10.1038/emi.2012.46 An ongoing outbreak of fungal meningitis in the United States has been traced to injections of contaminated corticosteroids produced by a compounding pharmacy.
openaire   +3 more sources

Contamination of Human Milk by Drugs and Chemicals [PDF]

open access: yesNutrition and Health, 1983
Three major areas are emphasized for a study of drug excretion in breast milk: maternal drug disposition, breast milk pharmacokinetics and neonatal drug elimination. The first two impact on drug dose to infant whereas the last area is crucial to drug accumulation in the infant.
openaire   +1 more source

Pharmacokinetics of hydroxymethylnitrofurazone and its parent drug nitrofurazone in rabbits

open access: yes, 2013
The prodrug hydroximethylnitrofurazone (NFOH) presents antichagasic activity with greatly reduced toxicity compared to its drug matrix nitrofurazone (NF). Besides these new characteristics, the prodrug was more active against the parasite T.
Davanço, Marcelo Gomes [UNESP]   +14 more
core   +4 more sources

Polysaccharides in Ocular Drug Delivery [PDF]

open access: yes, 2019
Polysaccharides, such as cellulose, hyaluronic acid, alginic acid, and chitosan, as well as polysaccharide derivatives, have been successfully used to augment drug delivery in the treatment of ocular pathologies.
Arto Urtti   +9 more
core   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Banknotes as a Source of Drug and Pharmaceutical Contamination of the Population

open access: yesToxics
This study investigates the potential contamination of cash register employees in the Slovak Republic with 148 selected pharmaceuticals, illicit drugs, and their metabolites. Of these, 42 substances were detected, and it was found that the target group—cashiers—regularly handle large volumes of banknotes, increasing their exposure to contaminants ...
Nina Petrovičová   +15 more
openaire   +3 more sources

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