Results 71 to 80 of about 212,176 (310)

Environmental contamination from clandestine drug manufacture

open access: yes, 2020
Drug abuse and drug seizures are on the rise across the United States. As drug prevalence increases, the public is more likely to come into contact with drugs, drug-contaminated locations, or sites of drug production.
Ciesielski, Austin Lee
core  

Drug-drug cross contamination in the Swisslog fully automated medication handling system

open access: yes, 2020
OBJECTIVE: The risk of drug-drug cross contamination in drug dispensing robots in hospital pharmacies causes cumbersome restraints to be put on the production of the robot for example by scheduling high-risk drugs to be dispensed at the end of the day ...
Skyggedal, Anne   +3 more
core   +1 more source

Diethylene glycol poisoning in Gurgaon, India, 1998

open access: yesBulletin of the World Health Organization, 2001
OBJECTIVE: To discover the cause of acute renal failure in 36 children aged 2 months to 6 years who were admitted to two hospitals in Delhi between 1 April and 9 June 1998.
Singh Jagvir   +11 more
doaj  

Contamination of a drug consumption room with drugs and potential risks for social health care workers

open access: yesHarm Reduction Journal
Background Studies have shown that contamination of surfaces by illicit drugs frequently occurs in forensic laboratories when manipulating seized samples as well as in pharmacies and hospitals when preparing medicinal drugs.
Flore Cuffaro   +8 more
doaj   +1 more source

Nitrosamine contamination of pharmaceuticals: Cases in Japan, formation mechanisms, detection methods, regulatory perspectives, and insights

open access: yesJournal of Pharmaceutical and Biomedical Analysis Open
In recent years, mutagenic nitrosamines, such as N-nitrosodimethylamine, have been detected in medicine. This has led to global product recalls and long-term supply suspensions by pharmaceutical companies and consequent clinical impacts.
Genichiro Tsuji   +7 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

The effect of bambermycin, carbadox, chlortetracycline and olaquindox on antibiotic resistance in intestinal coliforms: a new animal model [PDF]

open access: yes, 1984
Groups of germ-free mice kept in isolators and associated with faecal microflora from piglets were continuously given either water or a solution of one of the following: chlortetracycline (20 micrograms/ml), carbadox (50 micrograms/ml), olaquindox (50 ...
Corpet, Denis E., D E Corpet
core  

Simian virus 40, poliovirus vaccines, and human cancer: research progress versus media and public interests

open access: yesBulletin of the World Health Organization, 2000
From 1955 through early 1963, millions of people were inadvertently exposed to simian virus 40 (SV40) as a contaminant of poliovirus vaccines; the virus had been present in the monkey kidney cultures used to prepare the vaccines and had escaped detection.
J.S. Butel
doaj  

Environmental Contamination with Hazardous Drugs in Quebec Hospitals

open access: yesThe Canadian Journal of Hospital Pharmacy, 2012
Since publication of the US National Institute for Occupational Safety and Health alert on hazardous drugs in 2004, many health care organizations have reviewed their procedures for handling hazardous drugs. Occupational exposure may occur when handling, compounding, or administering a drug considered to be hazardous, at any stage from storage to waste
Jean-François, Bussières   +4 more
openaire   +3 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

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