Results 51 to 60 of about 212,176 (310)

Occupational Exposure to Antineoplastic Drugs: Identification of Job Categories Potentially Exposed throughout the Hospital Medication System

Safety and Health at Work, 2011
Objectives: Studies examining healthcare workers’ exposure to antineoplastic drugs have focused on the drug preparation or drug administration areas. However, such an approach has probably underestimated the overall exposure risk as the drugs need to be ...
Chun-Yip Hon, Kay Teschke, Prescillia Chua, Scott Venners, Lynne Nakashima   +4 more
doaj   +1 more source

Distance and destination of retail meat alter multidrug resistant contamination in the United States food system

Scientific Reports, 2023
Antibiotic-resistant infections are a global concern, especially those caused by multidrug-resistant (MDR) bacteria, defined as those resistant to more than three drug classes.
Gabriel K. Innes, Andrew N. Patton, Keeve E. Nachman, Joan A. Casey, G. Sean Stapleton, Alison G. Abraham, Lance B. Price, Sara Y. Tartof, Meghan F. Davis   +8 more
doaj   +1 more source

Analysis of Salmonella contamination and pathogenic characteristics in raw poultry meat in Fujian Province in 2020

Zhongguo shipin weisheng zazhi, 2021
ObjectiveTo investigate the contamination status, serotyping and antibiotic resistance of Salmonella in raw poultry meat in Fujian Province in 2020.MethodsSalmonella was isolated from 178 raw poultry meat samples according to GB 4789.4—2016, serotyping ...
FU Yixin, LI Minzhen, HONG Jinchun, ZHENG Yingxiang, CHEN Weiwei   +4 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Medicine recalls in Saudi Arabia: a retrospective review of drug alerts (January 2010–January 2019)

Future Journal of Pharmaceutical Sciences, 2020
Background A new incidence of a substandard medicinal product is discovered weekly as stated by the World Health Organization (WHO) around the world. After discovering an incidence of a substandard medicinal product, a drug recall announced to remove the
Bushra T. AlQuadeib, Iman M. Alfagih, Ameera H. Alnahdi, Shadia M. Alharbi, Rawan A. Al-ahmari   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Assessment of contamination and drug resistance profiles of non-typhoid Salmonella in pig slaughtering industry in Shandong Province

Zhongguo shipin weisheng zazhi, 2023
ObjectiveTo understand the contamination and drug resistance characteristics of non-typhoidal Salmonella （NTS） during pig slaughter.MethodsA total of 170 carcasses and environmental samples were collected from two large-scale pig slaughterhouses in May ...
LI Bingyan, LIU Lisha, BAI Li, ZHAO Ge, MI Xiaoyun, WANG Junwei, SU Zhanqiang   +6 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Effectiveness of a Closed-System Transfer Device in Reducing Surface Contamination in a New Antineoplastic Drug-Compounding Unit: A Prospective, Controlled, Parallel Study. [PDF]

PLoS ONE, 2016
The objective of this randomized, prospective and controlled study was to investigate the ability of a closed-system transfer device (CSTD; BD-Phaseal) to reduce the occupational exposure of two isolators to 10 cytotoxic drugs and compare to standard ...
Nicolas Simon, Michèle Vasseur, Marine Pinturaud, Marion Soichot, Camille Richeval, Luc Humbert, Michèle Lebecque, Ousseini Sidikou, Christine Barthelemy, Pascal Bonnabry, Delphine Allorge, Bertrand Décaudin, Pascal Odou   +12 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source