Results 51 to 60 of about 2,428,128 (309)

Illicit drug contamination of the Bristol pound local currency

open access: yesForensic Science International, 2020
Reports have shown the prevalence of the contamination of banknotes with a number of different drugs. These studies have focused on investigating drug contamination levels on currency which is either nationally or even international distributed. To present there has been no studies undertaken on banknotes circulating in well-defined and limited ...
Paul Bowdler   +7 more
openaire   +2 more sources

Assessment of contamination and drug resistance profiles of non-typhoid Salmonella in pig slaughtering industry in Shandong Province

open access: yesZhongguo shipin weisheng zazhi, 2023
ObjectiveTo understand the contamination and drug resistance characteristics of non-typhoidal Salmonella (NTS) during pig slaughter.MethodsA total of 170 carcasses and environmental samples were collected from two large-scale pig slaughterhouses in May ...
LI Bingyan   +6 more
doaj   +1 more source

Contamination Assessment and Reduction Project (CARP), Summary of Accomplishments and Findings

open access: yes, 2007
The document was created for the Contamination Assessment and Reduction Project (CARP) November 2007 Conference and provides background information about the project and a summary of its accomplishments and findings.

core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Effectiveness of a Closed-System Transfer Device in Reducing Surface Contamination in a New Antineoplastic Drug-Compounding Unit: A Prospective, Controlled, Parallel Study. [PDF]

open access: yesPLoS ONE, 2016
The objective of this randomized, prospective and controlled study was to investigate the ability of a closed-system transfer device (CSTD; BD-Phaseal) to reduce the occupational exposure of two isolators to 10 cytotoxic drugs and compare to standard ...
Nicolas Simon   +12 more
doaj   +1 more source

Drug targeting to tumors using HPMA copolymers [PDF]

open access: yes, 2009
Copolymers based on N-(2-hydroxypropyl)methacrylamide (HPMA) are prototypic and well-characterized polymeric drug carriers that have been broadly implemented in the delivery of anticancer agents.
Dep Farmaceutische wetenschappen   +2 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Brief strategic family therapy for adolescent drug abuse. [PDF]

open access: yes, 2003
To ensure that treatment providers apply the most current scientifically supported approaches to their patients, NIDA has supported the development of the "Therapy Manuals for Drug Addiction" series.

core  

National drug-related public expenditure online resource.

open access: yes, 2021
This is the first set of national profiles that the EMCDDA has produced on drug-related public expenditure. The profiles are based on the sections on public expenditure provided by the 27 EU Member States, Croatia, Turkey and Norway in the national ...

core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

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