Results 101 to 110 of about 1,750,852 (307)
Reducing Adolescent Drug Abuse: Sociological Strategies for Community Practice [PDF]
, 1989 Strategies for community-based sociological practice are discussed. The role of the sociologist in helping communities to recognize a social problem is analyzed in the context of social construction of reality theory. Once a community accepts that it has
Watts, W. David
core +1 more source
Programmable biomaterials for dynamic and responsive drug delivery [PDF]
, 2016 Biomaterials are continually being designed that enable new methods for interacting dynamically with cell and tissues, in turn unlocking new capabilities in areas ranging from drug delivery to regenerative medicine. In this review, we explore some of the
Almquist, BD, Kiani, MT, Stejskalova, A
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Governor's Office of Drug Control Policy Five-Year Strategic Plan, July 1, 2013-June 30, 2018 [PDF]
, 2014 The Office of the Drug Policy Coordinator is established in Chapter 80E of the Code of Iowa. The Coordinator directs the Governor’s Office of Drug Control Policy; coordinates and monitors all statewide counter-drug efforts, substance abuse treatment ...
core
Modelling parasite drug resistance: lessons for management and control strategies [PDF]
Tropical Medicine & International Health, 2001 Mathematical models of the evolution of drug resistance in infectious diseases are predominantly concentrated in three main areas: antimalarial, antibiotic and anthelmintic resistance. There appears to be little or no cross‐reference between them.
openaire +2 more sources
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
The Role of Early Maladaptive Schemas and Coping Strategies in Substance Dependency
Bilişsel Davranışçı Psikoterapi ve Araştırmalar Dergisi, 2014 Objective: The aim of this study was to evaluate the early maladaptive schemas and coping strategies of substance dependents. We hypothesized that substance dependents would have more maladaptive unhealthy schemas and would use less adaptive coping ...
Bikem Haciomeroglu +4 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Modelling the evolution of drug resistance in the presence of antiviral drugs
BMC Public Health, 2007 Background The emergence of drug resistance in treated populations and the transmission of drug resistant strains to newly infected individuals are important public health concerns in the prevention and control of infectious diseases such as HIV and ...
Archibald Chris, Yan Ping, Wu Jianhong
doaj +1 more source
Multistep kinetic self-assembly of DNA-coated colloids
, 2013 Self-assembly is traditionally described as the process through which an initially disordered system relaxes towards an equilibrium ordered phase only driven by local interactions between its building blocks.
Di Michele, Lorenzo +5 more
core +1 more source