Results 41 to 50 of about 403,583 (300)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Cost-related nonadherence to prescription medications in Canada: a scoping review

Patient Preference and Adherence, 2018
Shikha Gupta,1 Mary Ann McColl,1 Sara J Guilcher,2 Karen Smith3 1School of Rehabilitation Therapy, Queen’s University, Kingston, ON, Canada; 2Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada; 3Department of Physical ...
Gupta S, McColl MA, Guilcher SJ, Smith K
doaj  

Quantifying transmission fitness costs of multi-drug resistant tuberculosis

Epidemics, 2021
As multi-drug resistant tuberculosis (MDR-TB) continues to spread, investigating the transmission potential of different drug-resistant strains becomes an ever more pressing topic in public health.
Jūlija Pečerska, Denise Kühnert, Conor J. Meehan, Mireia Coscollá, Bouke C. de Jong, Sebastien Gagneux, Tanja Stadler   +6 more
doaj   +1 more source

Assessment of Health Care Costs and Total Baclofen Use Associated With Targeted Drug Delivery for Spasticity [PDF]

, 2023
Vishal Venkatraman, Charis A. Spears, Brittany Grace Futch, Zidanyue Yang, Beth Parente, Hui‐Jie Lee, Shivanand P. Lad   +6 more
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Promoting adverse drug reaction reporting: comparison of different approaches

Revista de Saúde Pública, 2016
OBJECTIVE To describe different approaches to promote adverse drug reaction reporting among health care professionals, determining their cost-effectiveness.
Inês Ribeiro-Vaz, Cristina Costa Santos, Ricardo Cruz-Correia   +2 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

National mass drug administration costs for lymphatic filariasis elimination. [PDF]

PLoS Neglected Tropical Diseases, 2007
BACKGROUND: Because lymphatic filariasis (LF) elimination efforts are hampered by a dearth of economic information about the cost of mass drug administration (MDA) programs (using either albendazole with diethylcarbamazine [DEC] or albendazole with ...
Ann S Goldman, Victoria H Guisinger, Moses Aikins, Maria Lourdes E Amarillo, Vicente Y Belizario, Bertha Garshong, John Gyapong, Conrad Kabali, Hussein A Kamal, Sanjat Kanjilal, Dominique Kyelem, Jefrey Lizardo, Mwele Malecela, Godfrey Mubyazi, P Abdoulaye Nitièma, Reda M R Ramzy, Thomas G Streit, Aaron Wallace, Molly A Brady, Richard Rheingans, Eric A Ottesen, Anne C Haddix   +21 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Costs of mass drug administration for scabies in Fiji.

PLoS Neglected Tropical Diseases, 2022
In 2019, the Murdoch Children's Research Institute in partnership with the Fiji Ministry of Health and Medical Services carried out an integrated mass drug administration (MDA) for the treatment of scabies and lymphatic filariasis in the Northern ...
Maria Mow, Li Jun Thean, Matthew Parnaby, Jyotishna Mani, Eric Rafai, Aalisha Sahukhan, Mike Kama, Meciusela Tuicakau, Joseph Kado, Lucia Romani, Daniel Engelman, Margot Whitfeld, John Kaldor, Andrew Steer, Natalie Carvalho   +14 more
doaj   +1 more source