Results 171 to 180 of about 1,617,093 (364)

Reformulating lipid nanoparticles for organ-targeted mRNA accumulation and translation

open access: yesNature Communications
Fully targeted mRNA therapeutics necessitate simultaneous organ-specific accumulation and effective translation. Despite some progress, delivery systems are still unable to fully achieve this.
Kexin Su   +16 more
doaj   +1 more source

Biohybrid Microrobots Based on Jellyfish Stinging Capsules and Janus Particles for In Vitro Deep-Tissue Drug Penetration [PDF]

open access: yesarXiv
Microrobots engineered from self-propelling active particles, extend the reach of robotic operations to submillimeter dimensions and are becoming increasingly relevant for various tasks, such as manipulation of micro/nanoscale cargo, particularly targeted drug delivery.
arxiv  

Design and evaluation of dry-coated tablets for colonic delivery of diclofenac sodium [PDF]

open access: yes, 2006
A colonic drug delivery system is required to protect a drug during its transit through the upper gastro-intestinal tract and allow its release in the colon.
Gavini, Elisabetta   +4 more
core  

Percutaneous Absorption: Controlled Drug Delivery For Topical or Systemic Therapy

open access: bronze, 1976
Jane E. Shaw   +2 more
openalex   +1 more source

Delivery of PLGA-Loaded Influenza Vaccine Microparticles Using Dissolving Microneedles Induces a Robust Immune Response

open access: yesPharmaceutics
Background: Influenza virus is one of the major respiratory virus infections that is a global health concern. Although there are already approved vaccines, most are administered via the intramuscular route, which is usually painful, leading to vaccine ...
Emmanuel Adediran   +10 more
doaj   +1 more source

Current and Future Issues in the Development of Spinal Agents for the Management of Pain. [PDF]

open access: yes, 2017
Targeting analgesic drugs for spinal delivery reflects the fact that while the conscious experience of pain is mediated supraspinally, input initiated by high intensity stimuli, tissue injury and/or nerve injury is encoded at the level of the spinal ...
Fisher, Casey J   +3 more
core  

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