Results 191 to 200 of about 413,917 (314)

Reconfigurable Nucleic Acid Nanoparticles with Therapeutic RNAi Responses to Intracellular Disease Markers

Advanced Functional Materials, EarlyView.
Many known diseases arise from dysregulated gene expression, and differentially expressed genes can serve as biomarkers to distinguish diseased cells from healthy tissues. In this study, reconfigurable nucleic acid nanoparticles (recNANPs) are introduced that can detect overexpressed cancer biomarkers and subsequently release RNAi inducers to silence ...
Yelixza I. Avila, Anh Ha, Morgan R. Chandler, Nathalia Leal Santos, Taejin Kim, Hannah S. Newton, Marina A. Dobrovolskaia, Kirill A. Afonin   +7 more
wiley   +1 more source

Nanotechnology-Based Drug Delivery Systems. [PDF]

Pharmaceutics
Kuskov AN, Kukovyakina EV, Krasnoselskaya EN.   +2 more
europepmc   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Drug Delivery Systems Targeting the Knee Microenvironment: A Prospective Strategy for Knee Osteoarthritis Treatment. [PDF]

Drug Des Devel Ther
Xia Y, Zhou Y, Liang B, Guo Y, Dai R, Ruan Z, Wang W, Zhou X, Li X, Wang T.   +9 more
europepmc   +1 more source

Solubility Enhancement of Lipophilic Drugs-Solid Self Micro-Emulsifying Drug Delivery System

, 2016
Pratiksha Sonawale, Amol Patil, Asmit Kamble, Mangesh A. Bhutkar   +3 more
openalex   +1 more source

Calcium Imparts Advanced Functionalities to Silk Hydrogels for Biofabrication and Biomedical Innovation

Advanced Functional Materials, EarlyView.
The addition of calcium ions to silk fibroin enhances the hydrogel properties and, when combined with visible light crosslinking, enables compatibility with advanced light‐based fabrication techniques. Calcium ions extend the shelf‐life of silk and facilitate the fabrication of multizonal, multilayered constructs for advanced stimuli‐responsive ...
Hien A. Tran, Anton Maraldo, Chi Cong Nguyen, Trinh Thi‐Phuong Ho, Lauryn Srethbhakdi, Habib Joukhdar, Quinn van Hilst, Syamak Farajikhah, Fariba Dehghani, Thanh Nho Do, Khoon S. Lim, Jelena Rnjak‐Kovacina   +11 more
wiley   +1 more source

Chitosan-Based Drug Delivery Systems for Targeted Chemotherapy in Colorectal Cancer: A Scoping Review. [PDF]

Mar Drugs
Piotrowska U, Szatko J, Nowakowska A, Klimaszewska E, Ogorzałek M, Sobczak M.   +5 more
europepmc   +1 more source

A REVIEW ON: MICROEMULGEL FOR TOPICAL DRUG DELIVERY SYSTEM

openalex   +1 more source

Development of self nanoemulsifying drug delivery system for black seed oil (Nigella sativa L.)

, 2020
Sani Ega Priani, Septiani Siti Maulidina, Fitrianti Darusman, Leni Purwanti, Dina Mulyanti   +4 more
openalex   +1 more source

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

Advanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer, Joanna M. Sadowska, Nadia Roumans, Christian Plank, Christopher H. Evans, Fergal J. O'Brien, Martijn van Griensven, Elizabeth R. Balmayor   +7 more
wiley   +1 more source