Results 151 to 160 of about 3,052,037 (266)

Problems of Drug Dependence, 1991: Proceeding of the 53rd Annual Scientific Meeting, The Committee on Problems of Drug Dependence, Inc.

, 1992

core   +1 more source

An Analysis of Treatment Preferences of Patients With Opioid Use Disorders: Findings From A Tertiary Drug Dependence Treatment Center in India. [PDF]

Addict Health
Singh S, Seth N, Brar MK, Verma A, Sarkar S, Dhawan A.   +5 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Problems of Drug Dependence 1990: Proceeding of the 52nd Annual Scientific Meeting, The Committee on Problems of Drug Dependence, Inc.

, 1991

core   +1 more source

A case report of pregabalin misuse leading to drug dependence. [PDF]

Front Psychiatry
Luo Y, Zhou X, Xiang A, Zeng Y, Luo J, Zhou B, Guo N, Zhou X.   +7 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Problems of Drug Dependence, 1995: Proceedings of the 57th Annual Scientific Meeting of the College on Problems of Drug Dependence, Inc.

, 1996

core   +1 more source

Adolescents, Drugs, and COVID-19: Special Challenges During the Pandemic

Indian Journal of Psychological Medicine, 2021
Gayatri Bhatia, Biswadip Chatterjee, Anju Dhawan   +2 more
doaj   +1 more source

Home-based detoxification for individuals with alcohol or drug dependence: A systematic review of the recent literature. [PDF]

Drug Alcohol Rev
Rens E, Ceelen A, Martens N, Van Camp L, Destoop M.   +4 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source