Results 161 to 170 of about 3,052,037 (266)

Problems of Drug Dependence, 1997: Proceedings of the 59th Annual Scientific Meeting of the College on Problems of Drug Dependence, Inc.

, 1998

core   +1 more source

Effects of different exercise types on craving in substance use disorder patients with drug dependence -network meta-analysis and dose-response relationships based on frequentist and Bayesian models. [PDF]

Addict Sci Clin Pract
Wang C, Yang Y, Wang K, Sun L, Liu SQ, Luo J.   +5 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Problems of Drug Dependence, 1996: Proceedings of the 58th Annual Scientific Meeting of the College on Problems of Drug Dependence, Inc.

, 1997

core   +1 more source

Training toolkit on drug policy advocacy.

, 2013
This training toolkit has been developed by the International Drug Policy Consortium (IDPC) and the Eurasian Harm Reduction Network (EHRN) to build the capacity of civil society organisations for engaging with, and influencing, drug policy making ...

core  

Drug dependence in cancer is exploitable by optimally constructed treatment holidays. [PDF]

Nat Ecol Evol
Maltas J, Killarney ST, Singleton KR, Strobl MAR, Washart R, Wood KC, Wood KB.   +6 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Problems of Drug Dependence, 1993: Proceedings of the 55th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. Volume II: Abstracts

, 1994

core   +1 more source

‘Civil society involvement in drug policy’ webinar.

, 2018
On 30th November 2018, Ana Liffey Drug Project hosted a webinar about Civil Society Involvement in Drug Policy. The event included interviews with: Anna Quigley (CityWide) Tony Duffin (Ana Liffey Drug Project) Aoife Frances (National Family Support ...

core  

Exploring the progression of drug dependence in a methamphetamine self-administration rat model through targeted and non-targeted metabolomics analyses. [PDF]

Sci Rep
Song SH, Kim S, Jang WJ, Ryu IS, Jeong CH, Lee S.   +5 more
europepmc   +1 more source