Results 181 to 190 of about 3,052,037 (266)

Problems of Drug Dependence, 1998: Proceedings of the 60th Annual Scientific Meeting of the College on Problems of Drug Dependence, Inc.

, 1999

core   +1 more source

If Drug Treatment Works So Well, Why Are So Many Drug Users in Prison? [PDF]

This paper examines the effectiveness of drug courts to reduce the size of the incarcerated drug-offending population using data from the Survey of Inmates in State Correctional Facilities and the Survey of Inmates in Local Jails.
Harold Pollack, Eric L. Sevigny, Peter Reuter   +2 more
core  

Drug dependence in patients with chronic pain: A retrospective study. [PDF]

Medicine (Baltimore), 2018
Tetsunaga T, Tetsunaga T, Nishida K, Kanzaki H, Misawa H, Takigawa T, Shiozaki Y, Ozaki T.   +7 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Problems of Drug Dependence, 2002: Proceedings of the 64th Annual Scientific Meeting of the College on Problems of Drug Dependence, Inc.

, 2003

core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Role of venlafaxine in relapse to methamphetamine seeking. Potential treatment option for drug dependence. [PDF]

Saudi Med J, 2019
Althobaiti YS.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Problems of Drug Dependence, 1994: Proceedings of the 56th Annual Scientific Meeting of the College on Problems of Drug Dependence, Inc. : Volume II: Abstracts

, 1994

core   +1 more source

Staff perceptions of prescription and over-the-counter drug dependence services in England: a qualitative study. [PDF]

Addict Sci Clin Pract, 2019
Coombes H, Cooper RJ.
europepmc   +1 more source