Results 301 to 310 of about 2,938,349 (358)

Impact of enhanced leaf model on dose calculation accuracy in single‐isocenter multitarget stereotactic radiosurgery treatments

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Single‐isocenter multitarget (SIMT) radiosurgery has become increasingly popular as advancement in planning and delivery systems have made this approach clinically viable. With targets varying in size and distance from isocenter, SIMT plans are highly complex with dynamic multileaf collimator (MLC) motion.
Hem Moktan, Hongyu Jiang, H. Harold Li, Kenny Guida   +3 more
wiley   +1 more source

Structure-Based Drug Design with a Deep Hierarchical Generative Model. [PDF]

J Chem Inf Model
Weller JA, Rohs R.
europepmc   +1 more source

Evaluating the use of diagnostic CT with flattening filter free beams for palliative radiotherapy: Dosimetric impact of scanner calibration variability

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Palliative radiotherapy comprises a significant portion of the radiation treatment workload. Volumetric‐modulated arc therapy (VMAT) improves dose conformity and, in conjunction with flattening filter free (FFF) delivery, can decrease treatment times, both of which are desirable in a population with a high probability of retreatment ...
Madeleine L. Van de Kleut, Lesley A. Buckley, Elsayed S. M. Ali   +2 more
wiley   +1 more source

The future of G protein-coupled receptor therapeutics: Apelin receptor acts as a prototype for the advancement of precision drug design. [PDF]

Clin Transl Med
Wang WW, Ji SY, Xu P, Zhang Y, Zhang Y.
europepmc   +1 more source

Evaluation of the effect of metal stents on dose perturbation in the carbon beam irradiation field

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Propose Carbon ion therapy is indicated for cases in which stents have been inserted, such as bile ducts, but the effect of metal stents on carbon ion therapy is unclear. In this study, the dose perturbation of carbon ion therapy caused by metallic bile duct stents was evaluated by dosimetry. Materials and methods Five different types of metal
Yuya Miyasaka, Tetsuya Ishizawa, Yoshihito Nawa, Hikaru Souda, Shohei Kawashiro, Hongbo Chai, Miyu Ishizawa, Hiraku Sato, Takeo Iwai   +8 more
wiley   +1 more source

Feasibility of the inhibitor development for cancer: A systematic approach for drug design. [PDF]

PLoS One
Jiang Y, Liu L, Geng Y, Li Q, Luo D, Liang L, Liu W, Ouyang W, Hu J.   +8 more
europepmc   +1 more source

JACMP 2005–2009

Journal of Applied Clinical Medical Physics, EarlyView.
Timothy D. Solberg
wiley   +1 more source

Commissioning of Halcyon enhanced leaf model in the Eclipse treatment planning system: Focus on simple slit fields and VMAT dose calculation

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose The dual‐layer multileaf collimator (MLC) in Halcyon adds complexities to the dose calculation process owing to the variability of dosimetric characteristics with leaf motion. Recently, an enhanced leaf model (ELM) was developed to refine the MLC model in the Eclipse treatment planning system. This study investigates the performance of
Ryohei Miyasaka, Mari Shirai, Mitsunobu Igari, Yume Kojima, Yuki Kozawa, Toru Kawachi, Ryusuke Hara   +6 more
wiley   +1 more source

Three-Dimensional Printing Technology in Drug Design and Development: Feasibility, Challenges, and Potential Applications. [PDF]

J Pers Med
Simon MC, Laios K, Nikolakakis I, Papaioannou TG.   +3 more
europepmc   +1 more source

JACMP 2020–2024

Journal of Applied Clinical Medical Physics, EarlyView.
Susan L. Richardson
wiley   +1 more source