Results 221 to 230 of about 1,359,668 (353)

Small molecule drug discovery for Ebola virus disease. [PDF]

RSC Med Chem
Durante D, Murugesh V, Kalanquin T, Gaisina IN, Rong L, Moore TW.   +5 more
europepmc   +1 more source

The value of plants used in traditional medicine for drug discovery.

, 2001
Daniel S. Fabricant, N.R. Farnsworth
openalex   +1 more source

The Integration of High Throughput Technologies for Drug Discovery [PDF]

, 2001
Gregory P. Sabbatini, William A. Shirley, David L. Coffen   +2 more
openalex   +1 more source

Behavioral Sciences and Drug Discovery [PDF]

, 2011
Enna, Sam
core   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Ophthalmic drug discovery and development using artificial intelligence and digital health technologies. [PDF]

NPJ Digit Med
Cheng H, Wong JLY, Quek CWN, Goldberg JL, Mahajan VB, Wong TY, Mehta JS, Ting DSW, Ting DSJ.   +8 more
europepmc   +1 more source

Significance of the human genome sequence to drug discovery

, 2001
Olivier Grenet
openalex   +1 more source

The integration of functional genomics, combinatorial chemistry and nanotechnology into a miniaturized drug discovery process [PDF]

, 2001
Manfred Auer
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

AI-Driven Drug Discovery: A Comprehensive Review. [PDF]

ACS Omega
Ferreira FJN, Carneiro AS.
europepmc   +1 more source