Results 241 to 250 of about 5,239,733 (368)

Metabolomics and Pharmacometabolomics: Advancing Precision Medicine in Drug Discovery and Development. [PDF]

Metabolites
Stolaki EV, Psatha K, Aivaliotis M.
europepmc   +1 more source

An Introduction to Electrospray Ionization and Matrix Assisted Laser Desorption/ Ionization Mass Spectrometry: Essential Tools in the Modern Drug Discovery Process

, 1998
Ashit K. Ganguly, BIRENDRA N. PRAMANIK
openalex   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Bioinformatics-Driven Drug Discovery for Breast Cancer: A Focus on Natural Compounds [PDF]

Ruquaiya Quddus
openalex   +1 more source

Targeting Autophagy In Disease: Recent Advances In Drug Discovery

, 2020
Dasol Kim, Hui‐Yun Hwang, Ho Jeong Kwon   +2 more
openalex   +2 more sources

A decade in drug discovery [PDF]

Nature Reviews Drug Discovery, 2012
openaire   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Graph neural networks driven acceleration in drug discovery. [PDF]

Acta Pharm Sin B
Wang R, Zhuang C.
europepmc   +1 more source

DIAGNOSIS OF LUNG CANCER BY USING HRCT, DRUG DISCOVERY BY USING HAEMOTOLOGY AND MICROSCOPY TECHNIQUES UNDER THE ANALYTE LEVODOR

Ayesha Jabeen,Sadia Malik,Kiran Aslam,Arooj Shaheen,Saima Batool,Munir Malik,Dr. Farooque Ahmad Haidari,Hafeez Ullah,Afshan Shahzadi,Kinza Saleem
openalex   +1 more source

Discovery of Drug-like Inhibitors of the Human Caf1/CNOT7 poly(A)-Selective Nuclease Using Compound Screening [PDF]

Ishwinder Kaur, Lubna Hashmi, Peter M. Fischer, G. Sebastiaan Winkler   +3 more
openalex   +1 more source