Results 41 to 50 of about 1,942,013 (293)
Advanced Science, EarlyView.Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li +7 more
wiley +1 more source
Dermatology Online Journal, 2009 A 78-year-old man presented with an eight-month history of folliculocentric, pink, hyperkeratotic papules and plaques with thick white scale that involved the entire body, with confluence on the buttocks and genitalia. A biopsy specimen demonstrated superficial and focal, mild perivascular and perifollicular, band-like lymphocytic infiltrate and ...
Brauer, Jeremy +3 more
openaire +4 more sources
Asia-Pacific Journal of Chemical Engineering, EarlyView.ABSTRACT Air pollution from sulfur dioxide (SO2) emissions poses significant threats to environmental sustainability, public health, and climate change efforts. Despite advances in monitoring and regulatory frameworks, traditional methods often fall short in accuracy, scalability, and efficiency.
Turkan Kopac
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective Hydroxychloroquine (HCQ) nonadherence in systemic lupus erythematosus (SLE) stemming from decision complexities can be improved with shared decision‐making (SDM) tools clarifying benefits and harms. This study aimed to develop and evaluate HCQ‐SAFE, a pictogram‐based SDM tool during SLE visits.
Caroline Packee +8 more
wiley +1 more source
Fixed Eruptions: Drug, food, and what more?
Clinical Dermatology ReviewFixed drug eruption (FDE) is a common entity encountered in our day-to-day clinical practice. It is a T-cell-dependent pathway with induction of interferon-gamma-producing CD8+ T-cells in the dermis and epidermis.
Prabhakar Mallikarjuna Sangolli +1 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun +4 more
wiley +1 more source
Patch Testing in Non-Immediate Drug Eruptions
Allergy, Asthma & Clinical Immunology, 2008 The present review addresses the literature regarding the sensitivity and specificity of the various diagnostic methods for evaluating non-immediate (ie, occurring more than 1 hour after drug administration) hypersensitivity reactions associated with β ...
Romano Antonino +4 more
doaj +1 more source
Dermatologica Sinica, 2021 Background: Plasmacytoid dendritic cells (pDCs) are implicated in the reactivation of human herpesvirus 6 (HHV-6) in drug reaction with eosinophilia and systemic symptoms (DRESS).
Shao-Hsuan Hsu +6 more
doaj +1 more source
Impact of hematological markers in prediction of severity of cutaneous drug eruptions
, 2023 Background Recognition of parameters to predict severity of drug eruptions can be helpful in early intervention in severe cases. In this study, we evaluate the role of hematological factors including neutrophil-to-lymphocyte ratio (NLR) and platelet-to ...
Mahin Aflatoonian +5 more
core +1 more source
Evaluating a virtual paediatric adverse drug reaction clinic
British Journal of Clinical Pharmacology, EarlyView.Aims Adverse drug reactions (ADRs) are a common problem in paediatric health care. There is limited access to expertise in the evaluation and management of potential ADRs in children, limiting access to these services and creating delays in assessment and management.
Emily Hauck +2 more
wiley +1 more source