Results 191 to 200 of about 205,639 (219)

Toward Personalized Theranostics: A Modular PET Platform for Antibody‐Based Imaging and Therapy

Advanced Science, EarlyView.
This modular, site‐specific antibody platform enables customizable conjugates for PET imaging and therapy. Interchangeable payloads – including radiometals, cytotoxics, and fluorophores – support adaptable, multimodal applications with limited off‐target effects. In vivo, the DFO/DOTAGA bischelate immunoconjugate provided clear tumor delineation in PET/
Delphine Vivier, Megane Grah Kple, Julen Ariztia, Marion Leroux, Mathieu Moreau, Michael Claron, Maxime Cheveau, Adam Laouafa, Agnieszka Kownacka, Camille Petitot, John Simonet, Alexandre M. M. Dias, Sophie Poty, Charles Truillet, Bertrand Collin, Alexandra Oudot, Franck Denat   +16 more
wiley   +1 more source

Reimagining Spinal Surgery at the Nanoscale: Smart Implants, Targeted Therapies, and Translational Challenges. [PDF]

Biology (Basel)
Pang AS, Pang KY, Liau ZQG, Kaliya-Perumal AK, Oh JY, Srinivasan DK.   +5 more
europepmc   +1 more source

Redefining drug discovery: AI-driven strategies for efficient cancer therapeutics. [PDF]

Front Oncol
De D, Chakraborty S, Banerjee S.
europepmc   +1 more source

Nanoparticle-Mediated Lutein Delivery for Diabetic Retinopathy: From Blood-Retinal Barrier Crossing to Neurovascular Unit Protection. [PDF]

Int J Nanomedicine
Wang Y, Xu W, Xu Y.
europepmc   +1 more source

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)-VK4-116, as a Non-Opioid Medication for the Treatment of Opioid Use Disorder. [PDF]

Med Res Rev
Wu CK, Lin YC, Huang J, Ding B, Terse P, Nandre R, Jin H, Congdon M, Shen K, Sanderson P, Tawa G, Mounaud S, Santis M, Lo D, Ottinger EA, Newman AH.   +15 more
europepmc   +1 more source

Functional Delivery of Nanoimmunotherapies in Pancreatic Ductal Adenocarcinoma: A Barrier-Informed Pharmaceutics Framework. [PDF]

Pharmaceutics
Xu B, Wei D, Tao K, Wang Y.
europepmc   +1 more source

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Antibody–Drug Conjugates: Smart Chemotherapy Delivery Across Tumor Histologies

Ca-A Cancer Journal for Clinicians, 2022
Shanu Modi, Javier Cortes, Jean-Charles Soria   +2 more
exaly