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Drug hypersensitivity reactions (DHRs) are a matter of great concern, both for outpatient and in hospital care. The evaluation of these patients is complex, because in vivo tests have a suboptimal sensitivity and can be time‐consuming, expensive and ...
C. Mayorga+20 more
semanticscholar +1 more source
The immunological basis of purpura due to drug hypersensitivity. [PDF]
Ackroyd Jf
openalex +2 more sources
Classification of Drug Hypersensitivity into Allergic, p-i, and Pseudo-Allergic Forms
Drug hypersensitivity reactions (DHR) are clinically and functionally heterogeneous. Different subclassifications based on timing of symptom appearance or type of immune mechanism have been proposed. Here, we show that the mode of action of drugs leading
W. Pichler, O. Hausmann
semanticscholar +1 more source
Drug Hypersensitivity in Daily Practice
Adverse drug reactions can affect up to 25% of outpatients and 10–20% of hospitalized patients. They are an important public health issue due to the potential of fatal outcomes. They are increasingly common in daily practice, but ascertaining whether the
Gatot Soegiarto
doaj +1 more source
The Japanese success rate for alcoholism treatment is approximately 30%, indicating high relapse rates. Although “difficulty in life” is thought to contribute to alcoholics’ relapse, the characteristics of the phenomenon are unknown.
Ito, Keiko
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Molecular Mechanisms for Drug Hypersensitivity Induced by the Malaria Parasite's Chloroquine Resistance Transporter [PDF]
Mutations in the Plasmodium falciparum ‘chloroquine resistance transporter’ (PfCRT) confer resistance to chloroquine (CQ) and related antimalarials by enabling the protein to transportthese drugs away from their targets within the parasite’s digestive ...
Baker, Eileen+6 more
core +1 more source
A new mechanism of hypersensitive transport in tilted sharp ratchets induced by noise flatness [PDF]
The noise-flatness-induced hypersensitive transport of overdamped Brownian particles in a tilted ratchet system driven by multiplicative nonequilibrium three-level Markovian noise and additive white noise is considered. At low temperatures the enhancement of current is very sensitive to the applied small static tilting force. It is established that the
arxiv
Estimation of Possible Selectivity and Sensitivity of a Cooperative System to Low-Intensive Microwave Radiation [PDF]
Recently, origins of non-deterministic behavior and free will in living systems obtain growing interest (see, e.g. Maye A, Hsieh C, Sugihara G, Brembs B (2007) Order in Spontaneous Behavior. PLoS ONE 2(5): e443. doi:10.1371/journal.pone.0000443). In this text, devoted to electromagnetic hypersensitivity, in n.2 and n.4, a possible physical mechanism of
arxiv
Drug hypersensitivity reactions (DHRs) affect an unknown proportion of the general population, and are an important public health problem due to their potential to cause life-threatening anaphylaxis and rare severe cutaneous allergic reactions.
Marta E. Torres+12 more
semanticscholar +1 more source
IntroductionBoth cellular and humoral responses are important for vaccine protection, but recommendations on immunosuppressants in dermatology are largely based on pre-pandemic experiences.
Kun-Lin Lu+39 more
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