Parametric Hypersensitivity and Transport in the Steady-State Open-System Holstein Model [PDF]
We demonstrate that the nonequilibrium steady state (NESS) of an open-system Holstein model with linear bias displays extreme sensitivity to the closed system parameters. This sensitivity is shown to correspond to avoided crossings in the closed system spectrum, as previously demonstrated in the Rabi model.
arxiv
Editorial: Women in NK and innate lymphoid cell biology
Alessandra Zingoni, Teresa Bellón
doaj +1 more source
Drug Recommendation toward Safe Polypharmacy [PDF]
Adverse drug reactions (ADRs) induced from high-order drug-drug interactions (DDIs) due to polypharmacy represent a significant public health problem. In this paper, we formally formulate the to-avoid and safe (with respect to ADRs) drug recommendation problems when multiple drugs have been taken simultaneously.
arxiv
On the Way to More Convenient Description of Drug-Plasma Protein Binding [PDF]
The theoretical case is considered where the total amount of plasma protein is conserved, but the drug is eliminated after its single application. After a single drug application at time t = 0, the total drug concentration is measured at times ti,...,tk and the total drug concentration at time ti is denoted by {\phi}i.
arxiv
Sensitivity of arabinosyladenine-resistant mutants of herpes simplex virus to other antiviral drugs and mapping of drug hypersensitivity mutations to the DNA polymerase locus [PDF]
Donald M. Coen+3 more
openalex +1 more source
Diffusive Mobile MC for Controlled-Release Drug Delivery with Absorbing Receiver [PDF]
Nanoparticle drug carriers play an important role in facilitating efficient targeted drug delivery, i.e., improving treatment success and reducing drug costs and side effects. However, the mobility of nanoparticle drug carriers poses a challenge in designing drug delivery systems.
arxiv
44 DRUG MODULATION OF INTESTINAL HYPERSENSITIVITY REACTIONS IN THE RAT [PDF]
M W Turner+4 more
openalex +1 more source
Investigating The Role of AEG-1 in Mouse Models of Pain [PDF]
Background: Astrocyte Elevated Gene 1 (AEG-1) is a multifunctional protein shown to be a regulator of transcription and multiple intracellular signaling pathways.
Bagdas, Deniz+4 more
core +1 more source
Sense and sensitisation: in vitro testing for hepatotoxic drug hypersensitivity [PDF]
Jeremy Woodward, James Neuberger
openalex +1 more source
A study was performed to assess the time between drug intake and drug induced hypersensitivity reaction for patients sensitive to nonsteroidal antiinflammatory drugs (NSAID) in clinical patient history and after oral provocation tests.
Giedre Grigiene, MD+2 more
doaj