Results 151 to 160 of about 223,933 (345)

Noncovalent interactions of drugs with immune receptors may mediate drug-induced hypersensitivity reactions [PDF]

, 2018
Drug-induced hypersensitivity reactions are instructive examples of immune reactions against low molecular weight compounds. Classically, such reactions have been explained by the hapten concept, according to which the small antigen covalently modifies ...
Gerber, Basil, Pichler, Werner
core  

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Drug Hypersensitivity Associated with Dental Treatments

Pesquisa Brasileira em Odontopediatria e Clínica Integrada
Objective: To characterize drug hypersensitivity associated with dental treatments. Material and Methods: Data from 5,302 dental patients extracted from the Faculty of Dental Medicine were used to investigate drug use history, drug hypersensitivity, and ...
Ricardo Dias de Castro, Mariana Bezamat, Alexandre Rezende Vieira   +2 more
doaj  

Afebrile vancomycin-induced delayed hypersensitivity suggestive of incomplete drug rash with eosinophilia and systemic symptoms syndrome: a case report

Journal of Medical Case Reports
Background Vancomycin-induced delayed hypersensitivity reactions are rare and typically accompanied by systemic symptoms such as fever, eosinophilia, and organ dysfunction, known as drug reaction with eosinophilia and systemic symptoms syndrome. However,
Chien-Hung Chou, Kun-Chuan Chang, Chi-Lan Kao, Kun-Jing Hong   +3 more
doaj   +1 more source

Nonsteroidal anti-inflammatory drug hypersensitivity in a pediatric severe asthmatic population. [PDF]

Pediatr Pulmonol, 2023
Hadley A, Slaven JE, Krupp NL, Kloepfer KM.   +3 more
europepmc   +1 more source

Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel, Christine van Linge, W. Joost Wiersinga, Ilse J. E. Kouijzer, Quirijn de Mast, Robert‐Jan Hassing, Danique J. H. Huijbens, Helen L. Leavis, Roger Schutgens, Coen Maas, Kit C. B. Roes, Frank L. van de Veerdonk, Roger Brüggemann   +12 more
wiley   +1 more source

Erratum to “An Updated Review of the Molecular Mechanisms in Drug Hypersensitivity”

Journal of Immunology Research, 2019
Chun-Bing Chen, Riichiro Abe, Ren-You Pan, Chuang-Wei Wang, Shuen-Iu Hung, Yi-Giien Tsai, Wen-Hung Chung   +6 more
doaj   +1 more source

A case report of ofloxacin induced fixed drug eruptions and hypersensitivity reaction

, 2017
Ashraffunnissa Fatima Farheen Kamal, Shrenik Vardhamane, Amreen Saba   +2 more
openalex   +2 more sources

Sense and sensitisation: in vitro testing for hepatotoxic drug hypersensitivity [PDF]

, 1997
Jeremy Woodward, James Neuberger
openalex   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source