Results 81 to 90 of about 105,471 (261)
Carboplatin hypersensitivity in relapsed ovarian carcinoma: A therapeutic challenge
Carboplatin and paclitaxel as doublet are the standard therapeutic option for advanced stage ovarian carcinoma in the first line as well as relapse. Carboplatin with its better toxicity profile has replaced cisplatin as the first line drug.
Avinash Pandey+6 more
doaj +1 more source
The Association of Increased Spontaneous Lymphocyte Transformation in Vitro with Clinical Manifestations of Drug Hypersensitivity [PDF]
Fred A. Gill
openalex +1 more source
Expert Perspectives on a Clinical Challenge: Hematologic Malignancies and Vasculitis
Systemic vasculitis describes a collection of rare diseases each caused by inflammation of blood vessel walls that can cause severe systemic complications [[3, 4]](#ref‐0003). The pattern of vascular inflammation and resultant damage is frequently variable and may be mimicked, or directly triggered, by infection or malignancy.
Michelle L. Robinette, Hetty E. Carraway
wiley +1 more source
Cutaneous drug hypersensitivity : Immunological and genetic perspective
Drug hypersensitivity is an unpredictable, immunologically mediated adverse reaction, clustered in a genetically predisposed individual. The role of "hapten concept" in immune sensitization has recently been contested by the "pharmacological interaction"
Kisalay Ghosh+3 more
doaj +1 more source
Objective To evaluate the applicability of the 2016 EULAR/ACR/PRINTO macrophage activation syndrome (MAS) classification criteria in patients with Still's disease (sJIA‐SD) treated with IL‐1‐targeted therapy and to assess the incidence of MAS in this context.
Remco G.A. Erkens+14 more
wiley +1 more source
Experimental and computational methods reveal unique diastereoconvergency in radical‐based catalytic aerobic carbooxygenation of 2‐fluoro‐3‐aryl‐allyl nitroacetates. Both (E)‐ and (Z)‐isomers are converted into α,α,β,β‐tetrasubstituted γ‐lactones with high syn‐selectivity, even without E/Z isomerization of the alkene unit.
Yanzong Lyu+4 more
wiley +1 more source
Aims This review aimed to synthesise the evidence related to the incidence of serious and non‐serious adverse events with the use of monoclonal antibodies (mAbs) among COVID‐19 patients. Methods Databases were searched from January 2020 to September 2023 for randomized clinical trials (RCTs) that used mAbs for the treatment of COVID‐19 regardless of ...
Htet Htet+6 more
wiley +1 more source
Editorial: Women in NK and innate lymphoid cell biology
Alessandra Zingoni, Teresa Bellón
doaj +1 more source
Aims Sulfamethoxazole–trimethoprim (SMX‐TMP) is a widely used antibiotic for treating bacterial infections, but its safety in adult outpatients remains understudied. This systematic review and meta‐analysis evaluated the safety profile of SMX‐TMP and identified critical research gaps.
Rebecca Preyra+4 more
wiley +1 more source