Results 81 to 90 of about 105,471 (261)

Carboplatin hypersensitivity in relapsed ovarian carcinoma: A therapeutic challenge

open access: yesIndian Journal of Medical and Paediatric Oncology, 2014
Carboplatin and paclitaxel as doublet are the standard therapeutic option for advanced stage ovarian carcinoma in the first line as well as relapse. Carboplatin with its better toxicity profile has replaced cisplatin as the first line drug.
Avinash Pandey   +6 more
doaj   +1 more source

Expert Perspectives on a Clinical Challenge: Hematologic Malignancies and Vasculitis

open access: yesArthritis &Rheumatology, Accepted Article.
Systemic vasculitis describes a collection of rare diseases each caused by inflammation of blood vessel walls that can cause severe systemic complications [[3, 4]](#ref‐0003). The pattern of vascular inflammation and resultant damage is frequently variable and may be mimicked, or directly triggered, by infection or malignancy.
Michelle L. Robinette, Hetty E. Carraway
wiley   +1 more source

Cutaneous drug hypersensitivity : Immunological and genetic perspective

open access: yesIndian Journal of Dermatology, 2011
Drug hypersensitivity is an unpredictable, immunologically mediated adverse reaction, clustered in a genetically predisposed individual. The role of "hapten concept" in immune sensitization has recently been contested by the "pharmacological interaction"
Kisalay Ghosh   +3 more
doaj   +1 more source

Impact of Interleukin‐1 Blockade on the Development of Macrophage Activation Syndrome in Still's Disease: Incidence and Diagnostic Validity of the EULAR/ACR/PRINTO 2016 MAS Classification Criteria

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To evaluate the applicability of the 2016 EULAR/ACR/PRINTO macrophage activation syndrome (MAS) classification criteria in patients with Still's disease (sJIA‐SD) treated with IL‐1‐targeted therapy and to assess the incidence of MAS in this context.
Remco G.A. Erkens   +14 more
wiley   +1 more source

Factors Controlling Diastereoselectivity and Reactivity in the Catalytic Aerobic Carbooxygenation of (E)‐2‐Fluoro‐3‐aryl‐allyl Nitroacetates

open access: yesChemistry – An Asian Journal, EarlyView.
Experimental and computational methods reveal unique diastereoconvergency in radical‐based catalytic aerobic carbooxygenation of 2‐fluoro‐3‐aryl‐allyl nitroacetates. Both (E)‐ and (Z)‐isomers are converted into α,α,β,β‐tetrasubstituted γ‐lactones with high syn‐selectivity, even without E/Z isomerization of the alkene unit.
Yanzong Lyu   +4 more
wiley   +1 more source

Adverse events associated with monoclonal antibodies used for treatment of COVID‐19: A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 5, Page 1306-1321, May 2025.
Aims This review aimed to synthesise the evidence related to the incidence of serious and non‐serious adverse events with the use of monoclonal antibodies (mAbs) among COVID‐19 patients. Methods Databases were searched from January 2020 to September 2023 for randomized clinical trials (RCTs) that used mAbs for the treatment of COVID‐19 regardless of ...
Htet Htet   +6 more
wiley   +1 more source

Editorial: Women in NK and innate lymphoid cell biology

open access: yesFrontiers in Immunology, 2023
Alessandra Zingoni, Teresa Bellón
doaj   +1 more source

Safety of sulfamethoxazole–trimethoprim for the treatment of bacterial infection in outpatient settings: A systematic review and meta‐analysis with active comparator disproportionality analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Sulfamethoxazole–trimethoprim (SMX‐TMP) is a widely used antibiotic for treating bacterial infections, but its safety in adult outpatients remains understudied. This systematic review and meta‐analysis evaluated the safety profile of SMX‐TMP and identified critical research gaps.
Rebecca Preyra   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy