Results 81 to 90 of about 84,588 (320)
An updated review of the immunological mechanisms of keloid scars
Frontiers in Immunology, 2023 Keloid is a type of disfiguring pathological scarring unique to human skin. The disorder is characterized by excessive collagen deposition. Immune cell infiltration is a hallmark of both normal and pathological tissue repair.
Chih-Chun Lee +31 more
doaj +1 more source
NeuroCADR: Drug Repurposing to Reveal Novel Anti-Epileptic Drug Candidates Through an Integrated Computational Approach [PDF]
arXiv, 2023 Drug repurposing is an emerging approach for drug discovery involving the reassignment of existing drugs for novel purposes. An alternative to the traditional de novo process of drug development, repurposed drugs are faster, cheaper, and less failure prone than drugs developed from traditional methods.
arxiv
Management of a Type I Hypersensitivity Reaction to IV Etoposide in a Woman with a Yolk Sac Tumor: A Case Report [PDF]
, 2011 Type I hypersensitivity reactions to intravenous administration of etoposide are extremely rare. Etoposide is an essential component of several chemotherapy regimens used in gynecologic oncology, and discontinuation of this drug during a course of ...
Amy Armstrong +6 more
core +3 more sources
The anti-IgE monoclonal antibody omalizumab as adjuvant treatment in desensitization to carboplatin in patients with ovarian cancer [PDF]
, 2021 • Ovarian cancer is the most lethal among gynecological cancers. • Carboplatin-based chemotherapy identifies as the main systemic treatment for ovarian cancer patients.
Antonuzzo, Lorenzo +12 more
core +1 more source
Nanotherapy for Neural Retinal Regeneration
Advanced Science, EarlyView.Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu +11 more
wiley +1 more source
Drug Hypersensitivity Syndrome toCarbamazepine and Human Herpes Virus 6 Infection: Case Reportand Literature Review [PDF]
, 2018 .: We describe a patient with a drug-induced hypersensitivity syndrome to carbamazepine and a concomitant active infection with human herpes virus 6 (HHV-6).
Battegay, E. +5 more
core
Genotyping for Severe Drug Hypersensitivity [PDF]
Current Allergy and Asthma Reports, 2014 Over the past decade, there have been significant advances in our understanding of the immunopathogenesis and pharmacogenomics of severe immunologically-mediated adverse drug reactions. Such T-cell-mediated adverse drug reactions such as Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), drug-induced liver disease (DILI) and other drug ...
Elizabeth J. Phillips +2 more
openaire +3 more sources
Large‐Scale Plasma Proteomics to Profile Pathways and Prognosis of Chronic Pain
Advanced Science, EarlyView.This study delineates both common and site‐specific proteins linked to various chronic pain conditions, elucidating their implications across molecular pathways and health status. These findings, particularly those proteins with genetic causal links to pain or predictive capabilities, have the potential to significantly benefit both research and ...
Ze‐Yu Li +17 more
wiley +1 more source
Advanced Science, EarlyView.From de novo engineered bioactive molecules BtP27 to the multifunctional supramolecular material BtP27@β‐CD with a sunflower‐shaped morphology: its pragmatic applications in augmenting foliar affinity, disrupting biofilms and T3SS, and managing rice pathologies. Abstract Conventional antimicrobials typically exhibit suboptimal deposition on rice leaves,
Xianfu Mu +6 more
wiley +1 more source
Frontiers in Pharmacology, 2020 Introduction: Being labelled as allergic to different drugs results in patients receiving other treatments, which are more toxic, less effective and more expensive.
Miriam Sobrino-García +29 more
doaj +1 more source