Results 91 to 100 of about 2,423,182 (300)

Desensitization Protocols for Hypersensitivity Induced by Cytotoxic Drugs;  Platinum Salts and Taxanes

Pakistan Armed Forces Medical Journal
With the expanding use of Platins and Taxanes for cancer patients, a highly concerning threat is observed in the form of Hypersensitivity reactions. To reduce hypersensitivity reactions, different desensitization protocols are formed.
Maha Zahid, Husnain Hamid, Numra Tahir, Aqsa Amjad, Irfan Bashir, Muhammad Jamshaid   +5 more
doaj   +1 more source

The processes of reform in Victoria’s alcohol and other drug sector, 2011-2014 [PDF]

, 2014
This paper explores issues and concerns related to the 2014 alcohol and other drug sector recommissioning process in Victoria. Overview In mid-2014, the Victorian Alcohol and Drug Association approached the Drug Policy Modelling Program, at the ...
Drug Policy Modelling Program
core  

Multiple drug hypersensitivity: normal Treg cell function but enhanced in vivo activation of drug-specific T cells

, 2011
Up to 10% of patients with severe immune-mediated drug hypersensitivity reactions have tendencies to develop multiple drug hypersensitivities (MDH). The reason why certain individuals develop MDH and the underlying pathomechanism are unclear.
Lerch, M, Groux-Keller, M, Park, B K, Naisbitt, D J, Wendland, T, Hausmann, O V, D. J. Naisbitt, T. Kawabata, Daubner, B, B. K. Park, M. Lerch, Pichler, W J, B. Daubner, W. J. Pichler, M. Groux-Keller, O. V. Hausmann, Kawabata, T, T. Wendland, Wendland, Thomas, Hausmann, Oliver, Pichler, Werner Joseph   +20 more
core   +1 more source

Cross‐Organ Multi‐Omics Profiling of Systemic Alterations in 5xFAD Mice and Changes Associated with Huanglian Jiedu Decoction Treatment

Advanced Science, EarlyView.
Cross‐organ multi‐omics reveals coordinated inflammatory and metabolic disturbances in 5xFAD mice. Huanglian Jiedu Decoction improves cognition and alleviates brain and liver abnormalities. Complementary hepatocyte–microglia conditioned‐medium experiments suggest PPAR‐γ involvement in treatment‐associated changes in microglial inflammation, providing ...
Wenya Gao, Jing Gao, Xiaohui Su, Xiangying Kong, Xiaolu Wei, Tunan Ding, Tiantian Guo, Shuangrong Gao, Yanyan Zhou, Junyi Zhou, Haiyu Zhao   +10 more
wiley   +1 more source

Vancomycin-Induced Stevens-Johnson Syndrome in a Boy Under 2 Years Old: An Early Diagnosis by Granulysin Rapid Test

Frontiers in Pediatrics, 2018
Stevens-Johnson syndrome (SJS) is a life-threatening disease, which is mainly ascribed to drugs, such as sulfonamides and psychoepileptics. In this article, we present a pediatric case of vancomycin-induced SJS and an alternative diagnostic algorithm ...
You-Cheng Lin, You-Cheng Lin, Ji-Nan Sheu, Ji-Nan Sheu, Wen-Hung Chung, Wen-Hung Chung, Ren-You Pan, Chu-Ju Hung, Jen-Jung Cheng, Yu-Ping Hsiao, Yu-Ping Hsiao   +10 more
doaj   +1 more source

Beyond the black box: drug- and device-associated hypersensitivity events

, 2010
Charles L Bennett1,2, Olatokunbo S Adegboro2, Elizabeth A Calhoun2, Dennis Raisch3,41Jesse Brown VA Medical Center, Chicago, IL, USA; 2University of Illinois School of Public Health, Chicago, IL, USA; 3University of New Mexico College of Pharmacy ...
Charles L Bennett, Olatokunbo S Adegboro, Elizabeth A Calhoun, Dennis Raisch   +3 more
core  

A simple screening approach to reduce B*5701-associated abacavir hypersensitivity on the basis of sequence variation in HIV reverse transcriptase [PDF]

, 2007
Background. Abacavir hypersensitivity is strongly associated with the human leukocyte antigen (HLA)–B*5701 allele; however, the cost of routine high-resolution HLA typing before initiation of therapy remains prohibitive.
Chui, C.K.S., Brumme, Z.L., Brumme, C.J., Yip, B., Montaner, J.S.G., Phillips, E.J., Harrigan, P.R.   +6 more
core  

Recurrent Neurodevelopmental Disorder Associated With a Dominant‐Negative TOP2B H63Y Variant

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT We describe a 7 year‐old boy with severe neurodevelopmental disorder, medically‐refractory epileptic encephalopathy, hyperkinetic movement disorder, hypotonia, cerebral and cerebellar atrophy and hypomyelination who was found to have a heterozygous de novo TOP2B NM_001330700.2:c.187C>T, p.(His63Tyr) variant.
Zong Yi Ha, Leticia Dinatto, Kirsten Meagher, Colleen Guimond, Jan M. Friedman, Peter C. Stirling, Millan S. Patel   +6 more
wiley   +1 more source

Clinical Characteristics, Healthcare Resource Utilization, and Costs of Patients with Generalized Pustular Psoriasis in Taiwan: A National Claims Database Study

Psoriasis: Targets and Therapy
Hsiu-Ting Chien,1 Chien-Yu Tseng,1 Chun-Wei Lu,2,3 Wen-Hung Chung,2,3 Fang-Ju Lin1,4,5 1Graduate Institute of Clinical Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan; 2Department of Dermatology, Drug Hypersensitivity Clinical ...
Chien HT, Tseng CY, Lu CW, Chung WH, Lin FJ   +4 more
doaj  

Drug Hypersensitivity in Daily Practice

Qanun Medika: Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya, 2019
Adverse drug reactions can affect up to 25% of outpatients and 10–20% of hospitalized patients. They are an important public health issue due to the potential of fatal outcomes. They are increasingly common in daily practice, but ascertaining whether the
Gatot Soegiarto
doaj   +1 more source