Results 221 to 230 of about 1,989,460 (302)

Population pharmacokinetics of tenofovir alafenamide delivered via an annual subdermal implant in South African women. [PDF]

Sci Rep
Beliveau M, Chang C, Lewis L, Letsoalo MP, Karim QA, Karim SSA, Marzinke MA, Moss JA, Gengiah TN, Baum MM.   +9 more
europepmc   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Polydopamine-Based Biomaterials in Oral Medicine: Applications, Mechanisms, and Translational Challenges. [PDF]

Int J Nanomedicine
Yang Z, Song W, Lv L, Zhai S, Liu Y, Cui H, Li X, Gao F, Chu S.   +8 more
europepmc   +1 more source

Covalent Functionalization of 2D Semiconductors: A Roadmap to Advanced Electronic Devices

Advanced Functional Materials, EarlyView.
This Review presents recent advances in the covalent functionalization strategies for two‐dimensional semiconductors and their implementation in modern technologies. Layered materials are modified through diverse molecular chemistries (e.g., thiols, diazonium salts, alkyl halides, and electron‐deficient species) to tailor their surface properties ...
Ramiro Quirós‐Ovies, Bin Han, Paolo Samorì   +2 more
wiley   +1 more source

Capsular Contracture Rates in Subfascial and Subglandular Breast Augmentation With Smooth vs Textured Implants. [PDF]

Aesthet Surg J
Abbott EN, Johnson J, Dorjsuren N, Savitz BL, Giannas E, Gutama BW, Maxwell GP, Perdikis G, Strock LL, Gabriel A.   +9 more
europepmc   +1 more source

A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

Advanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu, Yumin Wu, Xiang Gao, Tianlu Wang, Wanting Jia, Xueying Mei, Huanzhong Ji, Zongxi Wu, Yujie Liang, Xiang Li, Kan Li, Jingyuan Li, Guangsen Zheng, Guiqing Liao, Siyong Gao   +14 more
wiley   +1 more source

An Overview of In Vitro Release Methods for Long-Acting Injectable Products Based on PLGA. [PDF]

Methods Protoc
Lusina Kregar M, Krtalić I, Šagud I.
europepmc   +1 more source

Charting Morphotoxicity With Complementary Embryo Models

Advanced Healthcare Materials, EarlyView.
Three human embryo models of the peri‐implantation stages are exposed to a library of compounds. The (toxic) effects of the compounds are analyzed through automated image analysis pipelines. By evaluating the differential responses of the embryo models, this study underscores the importance of testing complementary embryo models to achieve robust and ...
Dorian G. Luijkx, Pauline L. Balder, Romy M. L. Verhagen, Vinidhra Shankar, Barry Jutten, Pinak Samal, Timo Rademakers, Clemens A. van Blitterswijk, Stefan Giselbrecht, Erik J. Vrij   +9 more
wiley   +1 more source

Management of Asymptomatic Breast Implant Rupture in Older Adult Patients: A Scoping Review, Discussion, and Recommendations. [PDF]

Plast Reconstr Surg Glob Open
Vernice NA, Boyd CJ, Hemal K, Amro C, Sorenson TJ, Park J, Karp NS, Cohen O, Choi M.   +8 more
europepmc   +1 more source