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Implantable Drug Delivery Systems
1998The use of implantable systems for chronic intraspinal delivery of medications has become an important tool in the management of a variety of clinical conditions, includ ing chronic pain due to cancer or nonmalignant causes as well as spasticity of spinal or cerebral origin.
Richard K Osenbach, Kim J Burchiel
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Implantable microchips for controlled drug delivery
The 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2005We report on the development of an implantable drug delivery system capable of delivering multiple individual doses. This product controls the release of potent therapeutic compounds that might otherwise require frequent injections. The system will provide stable, hermetic storage of therapeutic drugs, such as proteins and peptides, in solid, liquid ...
J M, Maloney, J T, Santini
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Intrathecal Drug Delivery: Implantation
2018Infusing medications directly into the cerebrospinal fluid (CSF) is an effective means of controlling chronic pain and minimizing long-term healthcare costs. Intrathecal therapy (ITT) is used to treat chronic severe intractable and refractory pain that does not respond to more conservative treatments.
Lucas W. Campos, Jason E. Pope
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Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies
Ca-A Cancer Journal for Clinicians, 2022Paolo Tarantino +2 more
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Implanted Drug Delivery Systems
2010Implanted Drug Delivery Systems are recommended to patients whose pain is poorly controlled with oral or parenteral medication or to those who experience drug related toxicities. Administration of intrathecal opioids and adjuvant medications allows reduction of up to 200% of oral or parenteral pain medication.1-3 In 1979, Wang and colleagues ...
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Absorption of Implanted Solid Drug
Journal of Pharmaceutical Sciences, 1962B E, BALLARD, E, NELSON
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Cancer epigenetics in clinical practice
Ca-A Cancer Journal for Clinicians, 2023Veronica Davalos, Manel Esteller
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