Results 161 to 170 of about 4,952,093 (307)

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Money, Meals, and Marketing in Medicine: A 13-Year Follow-Up Survey of Physicians. [PDF]

Clin Pharmacol Ther
Mooney H, Austad K, Campbell EG, Avorn J, Lu Z, Kesselheim AS.   +5 more
europepmc   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

DRLS, drug establishment registration and drug listing instruction booklet.

, 1991
Shipping list no.: 91-422-P.At head of title: DRLS, Drug Registration and Listing System.Mode of access ...
Center for Drug Evaluation and Research (U.S.). Drug Listing Branch.
core  

Modeling the impacts of budget reductions at the U.S. NIH on research and innovation. [PDF]

Npj Health Syst
Hasgul Z, Lee H, Jalali MS.
europepmc   +1 more source

Clinical Impact of MGMT Promoter Methylation in IDH‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang, Linxi Cao, Xiaodong Chen, Siqi Tong, Qinghui Zhu, Jun Yang, Song Lin, Yong Cui   +7 more
wiley   +1 more source

Evaluation of the Pharmaceutical Industry Investment Program [PDF]

With the expiry of the Pharmaceutical Industry Investment Program (PIIP) in 2004, the Commission was asked to conduct an evaluation of the program’s rationale, effectiveness and efficiency. The study commenced in August 2002.
Productivity Commission
core  

Characterizing public participation in Prescription Drug User Fee Act reauthorization, 2010-2021. [PDF]

Health Aff Sch
Ziaks TJ, Koda A, Ramachandran R, Ross JS, Schwartz JL.   +4 more
europepmc   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Environmental monitoring practices relevant to regenerative medicine manufacturing: Insights from a cross-sector survey of regulated facilities in Japan. [PDF]

Regen Ther
Mizuno M, Oono T, Takahashi K, Tsujimoto K, Tanigawa N, Nakamura Y, Nakamura H, Fujii K, Sekiya I.   +8 more
europepmc   +1 more source