Results 241 to 250 of about 7,440,138 (398)

Modelling of a double‐scattering proton therapy nozzle using the FLUKA Monte Carlo code and analysis of linear energy transfer in patients treated for prostate cancer

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Background The dose‐averaged linear energy transfer (LETD) in proton therapy (PT) has in pre‐clinical studies been linked to the relative biological effectiveness (RBE) of protons. Until recently, the most common PT delivery method in prostate cancer has been double‐scattered PT, with LETD only available through dedicated Monte Carlo (MC ...
Rasmus Klitgaard   +7 more
wiley   +1 more source

A review of artificial intelligence in brachytherapy

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy.
Jingchu Chen   +4 more
wiley   +1 more source

The Diffusion of Science-Driven Drug Discovery: Organizational Change in Pharmaceutical Research [PDF]

open access: yes
Recent work linking the adoption of key organizational practices to productivity raises an important question: if adoption increases productivity so dramatically, why does adoption across an industry take so long? This paper explores this question in the
Iain Cockburn   +2 more
core  

Commissioning of Halcyon enhanced leaf model in the Eclipse treatment planning system: Focus on simple slit fields and VMAT dose calculation

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose The dual‐layer multileaf collimator (MLC) in Halcyon adds complexities to the dose calculation process owing to the variability of dosimetric characteristics with leaf motion. Recently, an enhanced leaf model (ELM) was developed to refine the MLC model in the Eclipse treatment planning system. This study investigates the performance of
Ryohei Miyasaka   +6 more
wiley   +1 more source

Dose rate correction of a diode array for universal wedge field dosimetric verification

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To study the performance of MapCHECK 3 (MC3) in measuring universal wedge fields and propose a dose rate correction strategy to improve MC3 measurement accuracy. Materials and methods Universal wedge fields with different wedge angles and field sizes were measured at different depths using MC3.
Linyi Shen   +6 more
wiley   +1 more source

Monte Carlo modeling of radiation dose from radiation therapy with superficial x‐rays

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Introduction Superficial x‐rays (50–100 kVp) are used for treating non‐melanoma skin cancer and intraoperative radiation therapy (IORT). At these energies, the photoelectric effect significantly increases absorbed dose to bone compared to soft tissue.
Reham Barghash   +3 more
wiley   +1 more source

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