Results 91 to 100 of about 2,222,749 (351)

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Tobacco industry securing connections with political elites: a case study from Sri Lanka

Tobacco Induced Diseases, 2018
Background Ceylon Tobacco Company PLC (CTC), a British American Tobacco subsidiary, holds a de facto monopoly of the Sri Lankan cigarette market with a 99% market share.
Koswaththage Manuja Niranshi Perera, Karen Evans-Reeves, Peshani Risna Vithanage, Ishara Buddhika, Sameera Lakmal, Mahesh Rajasuriya, Anna Gilmore   +6 more
doaj   +1 more source

Clinical-pharmacological drug information center of Hannover Medical School: experiences and analysis from a tertiary care university hospital. [PDF]

Sci Rep, 2022
Heck J, Stichtenoth DO, Sabau R, Schröder C, Engeli S, Pape T, O'Connell N, Schumacher C, Krause O, Koop F.   +9 more
europepmc   +1 more source

Insufficient access to harm reduction measures in prisons in 5 countries (PRIDE Europe): a shared European public health concern [PDF]

, 2015
Background: Prisoners constitute a high-risk population, particularly for infectious diseases. The aim of this study was to estimate the level of infectious risk in the prisons of five different European countries by measuring to what extent the prison ...
Brentari, Cinzia, Holm, Karina, Jauffret-Roustide, Marie, Kolind, Torsten, Lion, Caroline, M Carrieri, Patrizia, Maguet, Olivier, Michel, Laurent, Moser, Andrea, Nava, Felice, Schiltz, Julie, Stöver, Heino, Van Malderen, Sara, Vanderplasschen, Wouter, Weltzien, Nadja   +14 more
core   +5 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

HSD20 The Changes of Prescription Patterns after Providing Therapeutic Duplication Dur(DRUG UTILIZATION REVIEW) Information in Outpatient Veterans at Vhs Medical Center [PDF]

, 2023
Jongyun Kim, Jordan S. Lim, Namkug Kim, Seunghee Baek, Hyun Gi Jeong   +4 more
openalex   +1 more source

Drug Possession Arrests Reported in Alaska, 1986–2017 [PDF]

, 2018
Underlying data is available in both Excel and PDF format. (Download below.)This fact sheet presents data on drug sale possession arrests reported by Alaska law enforcement agencies for the 32-year period 1986 to 2017. Overall, the drug possession arrest
Ervin, Benjamin
core  

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Moving to tobacco cultivation free livelihoods in Sri Lanka: lessons learned from India and Kenya

Tobacco Induced Diseases, 2018
Background The tobacco cultivation extend is 4480 Hectares (in year 2000) which account to 0.19% total agricultural land which it is not a government supported agriculture sector in Sri Lanka.
Pestheruweliyanaralalage Shehara Obin Simoni Cooray
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source