Results 111 to 120 of about 2,222,749 (351)

Unlocking access: a comprehensive analysis of medicines accessibility for rare diseases in Thailand

open access: yesOrphanet Journal of Rare Diseases
Introduction In Thailand, obtaining medicines for rare diseases presents significant challenges, with limited evidence highlighting these issues. Objectives To evaluate the accessibility of medicines and the extent of health insurance coverage for ...
Siriwat Suwattanapreeda   +6 more
doaj   +1 more source

Quantification of ADHD medication in biological fluids of pregnant and breastfeeding women with liquid chromatography: a comprehensive review

open access: yesFrontiers in Public Health
Attention Deficit/Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder that has long been considered a concern only in the pediatric population. However, symptoms often sustain into adulthood and may require medication.
Lena De Hondt   +5 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Descriptive Analysis of Recorded Phone Calls to Iran Drug and Poison Information Centers during 2011-2012 [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology, 2013
Background: Poisoning is one of the main causes of visits to emergency departments and hospitals in Iran. Drug and Poison Information Centers (DPIC) are reliable sources to guide poisoned patients and provide information about pharmaceutical agents. This
Talat Ghane   +2 more
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Progress [PDF]

open access: yes, 1989
Magazine reporting on the activities and programs of the University Hospital at Boston University Medical ...
Office of Publication Services, Boston University Medical Center
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The role of community leaders on rational drug use literacy: A structural equation modeling

open access: yesExploratory Research in Clinical and Social Pharmacy
Background: Irrational drug use remains a global health challenge, particularly in underserved communities with limited healthcare access. In Thailand, despite the Rational Drug Use (RDU) initiative, problems such as antibiotic misuse and selfmedication ...
Thunpitcha Sakpirom   +3 more
doaj   +1 more source

Cancer 2.0: A Summary of Recent Research [PDF]

open access: yes, 2010
Outlines findings on Internet access and use among cancer patients compared with other chronic disease patients, the demand for health information online, the role of social network sites, and implications for cancer treatment and ...
Susannah Fox
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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