Results 131 to 140 of about 2,222,749 (351)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Transfer of amenamevir into breast milk in breastfeeding patients with recurrent herpes simplex: study protocol for a single-arm, open-label study

open access: yesFrontiers in Pediatrics
BackgroundRecurrent herpes simplex (RHS) is a disease caused by reactivation of the herpes simplex virus. Patients with RHS are treated with anti-herpes virus medication.
Sachi Koinuma   +4 more
doaj   +1 more source

Reevaluating the Management of Chronic Temporomandibular Pain Are We Treating PTSD with Debridement and Lavage? [PDF]

open access: yes, 2004
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Bracha, Adam S.   +5 more
core  

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Nanotechnology Oversight: An Agenda for the New Administration [PDF]

open access: yes, 2008
Identifies how current laws can be applied or modified to provide needed oversight of nanotechnology and materials for public health and environmental protection.
J. Clarence Davies
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

After Heparin: Protecting Consumers From the Risks of Substandard and Counterfeit Drugs [PDF]

open access: yes, 2011
Based on case studies, examines globalization and quality management trends in pharmaceutical manufacturing, barriers to Federal Drug Administration oversight, and the security of pharmaceutical distribution.

core  

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