Results 211 to 220 of about 2,222,749 (351)

CellMiner cross-database (CellMinerCDB) version 2.2 for explorations of patient-derived cancer cell line pharmacogenomics. [PDF]

Nucleic Acids Res
Elloumi F, Reinhold WC, Varma S, Wang Y, Kinali M, Arakawa Y, Inoue Y, Aladjem MI, Pommier Y, Luna A.   +9 more
europepmc   +1 more source

An intranet database for a university hospital drug information center [PDF]

, 2001
Martin Dugas, Sonja Weinzierl, Alenka Pecar, Joerg Hasford   +3 more
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

African Natural Products Database (ANPDB): A resource for exploring the therapeutic potential of natural compounds from Africa. [PDF]

Nucleic Acids Res
Betow JY, Qaseem A, Bekono BD, Feng Y, Moumbock AFA, Simoben CV, Babiaka SB, Tanyi SA, Shu VA, Ndi AT, Onguéné PA, Metuge CS, Akame S, Eni DB, Namba-Nzanguim CT, Tjegbe MJM, Dikande MNL, Akeh PT, Balgah S, Meh CD, Ibezim A, Tabi IF, Malange YI, Ndingkokhar B, Njume LE, Telukunta KK, Amrani S, Ebob OT, Sippl W, Günther S, Ntie-Kang F.   +30 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Confidentiality of alcohol and other drug abuse treatment information for emergency department and trauma center patients.

, 2010
Richard C. Boldt
openalex   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Macrocycle-DB: a comprehensive database for macrocycle-based drug discovery. [PDF]

Nucleic Acids Res
Jiang M, Liu T, Hussain M, Luo Y, Zheng R, Hou T, Lu X, Zhou Y.   +7 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Prevalence of drug resistant tuberculosis and its associated factors among tuberculosis patients at wolkite health center in central Ethiopia. [PDF]

Sci Rep
Simieneh A, Dereje R, Misganaw T, Abebe GF.   +3 more
europepmc   +1 more source