Results 41 to 50 of about 1,398,928 (286)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Contribution of the Regional Drug Information Center Towards Drug Safety

open access: yesJournal of Nepal Medical Association, 2006
Drug related complications may lead to huge economic impact and cause significant morbidity and mortality. The present study analyzed the services provided by our Drug Information Center (DIC) in relation to drug safety.
Subish Palaian   +4 more
doaj   +1 more source

Do Continuing Medical Education Programs Improve Drug Prescribing Status in Iran? A Qualitative Study [PDF]

open access: yesمجله علوم پزشکی صدرا, 2019
Background: Holdingcontinuing medical education programs (CME) is one of the recommended global strategies for attaining rational drug prescribing by physicians.
Mahmood Keyvanara   +3 more
doaj   +1 more source

Regional drug information center disseminates educational materials related to the COVID-19 pandemic

open access: yesExploratory Research in Clinical and Social Pharmacy, 2021
Background: Drug information centers (DIC) play an important role in providing correct and scientifically supported information on medicinal products.
Jaqueline Rocha Borges dos Santos
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Characteristics of drug users who do or do not have care of their children

open access: yes, 2004
Aims - To compare the relative frequency of eight indicators of problem drug use and potentially adverse social circumstances in drug using parents and non-parents and to explore whether a profile based on these characteristics differs according to ...
Advisory Council on the Misuse of Drugs   +18 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Implementation of Drug Information Services at Colomadu II and Jaten II Health Centers, Karanganyar Regency

open access: yesIndonesian Journal of Pharmaceutical Education
Drug Information Service (DIS) is an activity provided by pharmacists to patients. However, some aspects of DIS are often not implemented, resulting in non-compliance and failure of therapy in patients.
Vivid Latri Sudarwati   +2 more
doaj   +1 more source

Wasted opportunities: Problematic alcohol and drug use among gay men and bisexual men [PDF]

open access: yes, 2009
This report describes the findings from a qualitative and quantitative study of alcohol and drug use among gay and bisexual men and other men that have sex with men (MSM) in England. The qualitative element describes the experiences and understandings of
Bourne, Adam   +3 more
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

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