Results 81 to 90 of about 2,627,867 (322)

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Evaluasi Pelayanan Informasi Obat Pada Pasien Tuberkulosis di Puskesmas Provinsi Banten

open access: yesIndonesian Journal of Pharmaceutical Education
Pharmacists have an obligation to carry out drug information services that are based on the interests of patients. Among the drug information services that must be provided by a pharmacist is Knowledge regarding the use of medications that are ...
Fajrin Noviyanto   +5 more
doaj   +1 more source

Access and use of interventions to prevent and treat malaria among pregnant women in Kenya and Mali: a qualitative study. [PDF]

open access: yes, 2015
BACKGROUND: Coverage of malaria in pregnancy interventions in sub-Saharan Africa is suboptimal. We undertook a systematic examination of the operational, socio-economic and cultural constraints to pregnant women's access to intermittent preventive ...
Achieng, Florence   +11 more
core   +6 more sources

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

The Relationship Between Pharmaceutical Services and Satisfaction of Customers Accessing Pharmacy Services in Denpasar [PDF]

open access: yes, 2014
Background and purpose: Pharmacetical care has been shifted from product or drug oriented paradigm into patient oriented to ensure that every custumer will be able get the most effective medication.
Arimbawa, E. (Eka)
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Developing client-based analyses for reporting on the alcohol and other drug treatment services [PDF]

open access: yes
This paper outlines intended analysis techniques to estimate the number and rate of clients receiving alcohol and other drug treatment, to explore patterns of drug use and pathways through treatment, and to explore the characteristics of different client

core  

Fusing drug enforcement: a study of the El Paso Intelligence Center [PDF]

open access: yes, 2015
This article examines the evolution of the El Paso Intelligence Center (EPIC), a key intelligence component of the Drug Enforcement Administration, to shed light on fusion efforts in drug enforcement.
Van Puyvelde, Damien
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Importance of early precautionary actions in avoiding the spread of COVID-19: Saudi Arabia as an Example

open access: yesSaudi Pharmaceutical Journal, 2020
Late in 2019, several cases of infection with a new strain of coronavirus were reported in China. This new strain was later officially named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by the World Health Organization (WHO).
Thamir M. Alshammari   +2 more
doaj   +1 more source

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