Results 171 to 180 of about 1,909,397 (348)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Interaction of benzodiazepine drugs with striatal dopaminergic neurons in the brain

, 1976
Kazuo Nakamura, Keiji Nakamura
openalex   +1 more source

Interaction between Doxycycline and some Antiepileptic Drugs [PDF]

, 1974
O. Penttilä, Pertti J. Neuvonen, Kimmo Aho, R. Lehtovaara   +3 more
openalex   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

The effect of ethanol on drug oxidations in vitro and the significance of ethanol–cytochrome P-450 interaction [PDF]

, 1973
Dominick L. Cinti, Robert Grundin, Sten Orrenius   +2 more
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Drug Interactions With Excessive Daytime Sleepiness Treatments. [PDF]

J Pharm Technol
Thomas SV, Malesker MA, Hilleman DE, Dewan NA.   +3 more
europepmc   +1 more source

Interactions Between Clonidine and α-Adrenoceptor Blocking Drugs on the Tachycardic Response to Stimulation of the Cardiac Nerve in Dogs

, 1979
P Mouillé, Anne‐Marie Huchet, Bernadette Lucet, Jacques E. Chelly, Henri Schmitt   +4 more
openalex   +1 more source

Drug Interactions in Patients on Long-term Oral Anticoagulant and Antihypertensive Adrenergic Neuron-blocking Drugs [PDF]

, 1972
Kate J. Starr, J C Petrie
openalex   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source