Results 201 to 210 of about 1,977,520 (346)

Curcumin in the Treatment of Kidney Disease: A Systematic Review with a Focus on Drug Interactions. [PDF]

Antioxidants (Basel)
Ofori-Attah E, Aning A, Simón L.
europepmc   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Host–Pathogen Interaction Mapping in Drug-Resistant Tuberculosis: A Systems Biology Framework for Dual Therapeutic Targeting [PDF]

Onwu Daniel Ocha, Anmol Singh, Yashi Bajpai, Akinlamilo Adeyemi Sunday, Adele Habiganuchi, Felix Oladunjoye Ibikunle   +5 more
openalex   +1 more source

A Modeling Investigation of the CYP1A Drug Interactions of Riluzole. [PDF]

Clin Transl Sci
Malik P, Mian P, Andrews J, Rosebraugh M, Ajroud-Driss S.   +4 more
europepmc   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Small RNA or oligonucleotide drugs and challenges in evaluating drug-drug interactions. [PDF]

Front Pharmacol
Cronin JM, Yu AM.
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Utility of physiologically based pharmacokinetic modeling in predicting and characterizing clinical drug interactions [PDF]

R. Foti
openalex   +1 more source

Molecular basis of vesicular monoamine transport and neurological drug interactions. [PDF]

Cell Rep
Ye J, Chen H, Ammerman A, Wang Y, Wang K, Xu J, Liu B, Li W.   +7 more
europepmc   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source