Results 201 to 210 of about 896,459 (312)
Solid-state NMR protocols for unveiling dynamics and (drug) interactions of membrane-bound proteins. [PDF]
Lasorsa A, van der Wel PCA.
europepmc +1 more source
We report that some menthol‐like cooling compounds, including (R)‐(‐)‐carvone, act as inhibitors of TAS2R31 and TAS2R43, which are taste receptors responsible for the intrinsic bitter aftertastes of saccharin and acesulfame K. However, there was little correlation between the intensity of the cooling sensation and the potency of bitterness inhibition ...
Miyuu Saito, Takumi Misaka
wiley +1 more source
LSA-DDI: Learning Stereochemistry-Aware Drug Interactions via 3D Feature Fusion and Contrastive Cross-Attention. [PDF]
Wang S, Yang C, Chen L.
europepmc +1 more source
Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi+5 more
wiley +1 more source
Dietary Supplements for Weight Loss and Drug Interactions. [PDF]
Rivas García F+3 more
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Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura+7 more
wiley +1 more source
Patients with dementia: prevalence and type of drug-drug interactions. [PDF]
Muñoz-Contreras MC+3 more
europepmc +1 more source