Results 241 to 250 of about 1,977,520 (346)

Drug-substrate interactions from a theory-based databank of transferable pseudoatoms and potential curves derived from advanced theoretical calculations.

, 2005
Philip Coppens, Anatoliy Volkov, Xue Li, P.M. Dominiak   +3 more
openalex   +2 more sources

Gaps in the detection of drug-drug interactions between antipsychotic and cardiometabolic medications: a multisource analysis. [PDF]

BMC Med
Yao H, Peng Z, Huang Y, Xiao S, Wu R.
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Characterization of Drug-Drug Interactions for Remdesivir, an Intravenous Antiviral for SARS-CoV-2, in Healthy Participants. [PDF]

Clin Transl Sci
Chang J, Kim A, Humeniuk R, Shaik NA, Winter H, Peng CC, Xiao D, Abdelghany M, Llewellyn J, Davies S, Golden K, Chen S, Hyland RH, Caro L.   +13 more
europepmc   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

ANALYSIS OF DRUG INTERACTIONS IN HYPERTENSIVE PATIENTS

Nascimento, Andrey, Lima, Gabriel, Giorgi, Nicolas, Nascimento, Paulo, Neto, Walter, Del Rey, Barbara   +5 more
openalex   +1 more source

Clozapine Drug-Drug Interactions and Individualized Dosing in Bipolar Disorder: A Model-Informed Precision Dosing Approach. [PDF]

Drug Des Devel Ther
Zhang Y, Wang J, Tian X, Zhang YJ, Li Y, He SM, Zhang C, Chen X, Wang DD.   +8 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

SGCL-DPI: structure-guided curriculum learning for drug-protein interaction prediction [PDF]

Othman Soufan
openalex   +1 more source