Results 251 to 260 of about 1,999,544 (345)

Evaluation of in vitro drug-drug interactions of ivermectin and antimalarial compounds. [PDF]

Malar J
Tipthara P, Kullasakboonsri R, Kobylinski KC, Tarning J.   +3 more
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Specifics of drug-drug interactions between rivaroxaban and a P-glycoprotein inhibitor depending on the <i>CYP3A4/A5</i> gene polymorphism in patients aged 80 years and older with non-valvular atrial fibrillation

М. С. Черняева, Irena Konstantinova, E. I. Baranovskaya, О. В. Головина, I. I. Sinitcina, П. О. Бочков, Sh. P. Abdullaev, Н. П. Денисенко, G. A. Sozaeva, К. Б. Мирзаев, N. V. Lomakin, Д. А. Сычев   +11 more
openalex   +2 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Silent Dangers in Elderly Pharmacotherapy: The Interplay of Polypharmacy, Multimorbidity, and Drug Interactions. [PDF]

J Eval Clin Pract
Ngcobo NN.
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Drug-drug interactions: A descriptive analysis of FDA adverse event reporting system. [PDF]

Medicine (Baltimore)
Alahmari A, Fatani S, Ahmed N.
europepmc   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Extracting drug-drug interactions from biomedical texts

BMC Bioinformatics, 2010
de Pablo-Sánchez César, Martínez Paloma, Segura-Bedmar Isabel   +2 more
doaj   +1 more source

Benzodiazepine (BZD) Use and Patient Safety: Opportunities for Community Pharmacy Involvement in the Management of Drug Interactions. [PDF]

Pharmacy (Basel)
Santana Ayala JR, Alberto Armas D, Hernández García V, Aguirre-Jaime A, Gutiérrez ÁJ, Paz-Montelongo S, Hardisson de la Torre A, Rubio Armendáriz C.   +7 more
europepmc   +1 more source