Results 261 to 270 of about 1,999,544 (345)

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Pharmacological risks of khat-oral antidiabetic drug interactions among patients at Gondar university referral hospital. [PDF]

Sci Rep
Mengesha AK, Ayele HS, Beyna AT, Gebiyaw ST, Tessema TA, Alemu MA, Haile TD.   +6 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Pharmacology and relevant drug interactions of metamizole. [PDF]

Br J Clin Pharmacol
Brinkman DJ, Hendriksen LC, Rigter IM, Hollmann MW.   +3 more
europepmc   +1 more source

Investigation of Drug-Excipients Interaction in the Formulation of Lafutidine-Ciprofloxacin Microcapsules

Anju Mishra
openalex   +2 more sources

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Drug–Drug Interactions

Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics, 2013
openaire   +3 more sources

Factors associated with drug-drug interactions involving citalopram in the UK Biobank. [PDF]

BJPsych Open
Laplace B, Wong WLE, Menchetti M, De Ronchi D, Fusar-Poli P, Fanelli G, MNESYS – Mood and Psychosis Sub-Project (Spoke 5), Serretti A, Lewis CM, Fabbri C.   +9 more
europepmc   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Gaps in the detection of drug-drug interactions between antipsychotic and cardiometabolic medications: a multisource analysis. [PDF]

BMC Med
Yao H, Peng Z, Huang Y, Xiao S, Wu R.
europepmc   +1 more source