Results 161 to 170 of about 471,442 (349)

Unlicensed and off label drug use in paediatric wards: prospective study [PDF]

, 1998
S. Turner, Aisling Longworth, Anthony J Nunn, Imti Choonara   +3 more
openalex   +1 more source

Getting Even Less than What They Paid for: The Plight of Generic Drug Consumers Under the Levine-Mensing Dichotomy [PDF]

, 2015
The Drug Price Competition and Patent Restoration Act of 1984, known as the Hatch-Waxman Amendments, allows manufacturers to begin developing generic versions of patented, brand-name pharmaceuticals while the patent terms are in force, and to bring those
Chandrashekar, Vikrama
core   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Developing a model of a professional veterinary drug label [PDF]

, 1996
Marilyn N. Martinez, Scott A. Brown, Dennis D. Copeland, G.K. Haibel, G. D. KORITZ, M.G. Riddell, Jim E. Riviere, Larry D. Rollins   +7 more
openalex   +1 more source

Reporting of Drug Benefit in FDA-Approved Prescription Drug Labeling. [PDF]

J Gen Intern Med, 2020
Desai B, Hong K, Powers JH, Doshi P.
europepmc   +1 more source

Required and Optional Labeling for Loose Tea for Sale [PDF]

, 2012
This is a guide to the content and format for labeling loose tea for sale as required by the U.S.
Fergerstrom, Marla, Hollyer, James R., Hu, C.Y.   +2 more
core  

\u3ci\u3eUnited States v. Caronia\u3c/i\u3e: Off-Label Drug Promotion and First Amendment Balancing [PDF]

, 2018
Off-label drug promotion is commonplace in the United States, but it is not without its dangers. While the Food, Drug, and Cosmetic Act does not explicitly ban off-label promotion, the Food & Drug Administration (FDA)— in order to protect consumers from ...
Rabinowitz, Daniel P.
core   +1 more source

The effect of kV imaging dose on PTV and OAR planning constraints in lung SBRT using stereoscopic/monoscopic real‐time tumor‐monitoring system

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Quantify the impact of additional imaging doses on clinical dose constraints during lung stereotactic body radiotherapy (SBRT) treatment utilizing stereoscopic/monoscopic real‐time tumor monitoring. Materials and Methods Thirty lung SBRT patients treated with the volumetric arc therapy technique were randomly selected from the ...
Ruwan Abeywardhana, Mike Sattarivand
wiley   +1 more source