Results 261 to 270 of about 454,627 (348)

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

Advanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer, Joanna M. Sadowska, Nadia Roumans, Christian Plank, Christopher H. Evans, Fergal J. O'Brien, Martijn van Griensven, Elizabeth R. Balmayor   +7 more
wiley   +1 more source

Design and Evaluation of Next-Generation HIV Genotyping for Detection of Resistance Mutations to 28 Antiretroviral Drugs Across 5 Major Classes Including Lenacapavir. [PDF]

Clin Infect Dis
Park SY, Takayama C, Ryu J, Sattah M, Badii Z, Kim JW, Shafer RW, Gorbach PM, Lee HY.   +8 more
europepmc   +1 more source

177Lu-labeled antibody-drug conjugate: a dual mechanistic treatment modality in solid tumors with heterogeneous antigen expression

Aiko Yamaguchi, Chisato Yamazaki, Yasuaki Anami, Summer Y. Y. Ha, Robert Ta, Wei Xiong, Ningyan Zhang, Zhiqiang An, Kyoji Tsuchikama, Charles Manning   +9 more
openalex   +1 more source

Mechanically Tunable Bone Scaffolds: In Vivo Hardening of 3D‐Printed Calcium Phosphate/Polycaprolactone Inks

Advanced Functional Materials, EarlyView.
A 3D bone scaffold with osteogenic properties and capable of hardening in vivo is developed. The scaffold is implanted in a ductile state, and a phase transformation of the ceramic induces the stiffening and strengthening of the scaffold in vivo. Abstract Calcium phosphate 3D printing has revolutionized customized bone grafting.
Miguel Mateu‐Sanz, Pablo Varela, Laura del‐Mazo‐Barbara, Irene Lodoso‐Torrecilla, Emilio Jiménez‐Piqué, Jordi Franch, Miguel Alaminos, Maria‐Pau Ginebra   +7 more
wiley   +1 more source

Food Compass Score vs FDA Healthy Labeling and Consumer Purchases: A Randomized Clinical Trial.

JAMA Netw Open
Fan B, Fuller K, Sharib JR, Pomeranz JL, Wang M, Wang L, Mozaffarian D, Cash SB.   +7 more
europepmc   +1 more source

Strengthening the Food and Drug Administration Office of Clinical Pharmacology's Labeling Authority. [PDF]

Clin Transl Sci
Ratain MJ, Strohbehn GW.
europepmc   +1 more source

Polysaccharides as drug carriers: High-performance size-exclusion chromatographic determination of FITC-labeled dextran and pullulan.

, 1996
Yoshiharu Kaneo, Tomochika Uemura, Tetsuro Tanaka, Satoshi Kanoh   +3 more
openalex   +2 more sources

Bicontinuous Microarchitected Scaffolds Provide Topographic Cues That Govern Neuronal Behavior and Maturation

Advanced Functional Materials, EarlyView.
A scalable biomimetic platform transforms bioinert poly(ethylene glycol) diacrylate into neuroinstructive matrices via integrating solvent transfer‐induced phase separation, microfluidics, and 3D bioprinting. Bicontinuous, hyperbolically curved microporous networks embedded within a fibrous construct elicit rapid adhesion, robust proliferation, and ...
Prince D. Okoro, Kevin Dalsania, Shiril B. Iragavarapu, Benjamin Dela Cruz, Aihik Banerjee, Merve Basaranbilek, Martin F. Haase, Bahman Anvari, Iman Noshadi   +8 more
wiley   +1 more source

Assessment of dispensing practices and patient's knowledge of dispensed medicines in a hospital pharmacy, Ethiopia. [PDF]

Sci Rep
Ambaye AS, Zewdie S, Siraj EA, Yayehrad AT, Addisu ZD, Kebede SY, Kassa MT, Endalifer BL.   +7 more
europepmc   +1 more source

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source