Results 271 to 280 of about 458,270 (348)

A comparison of the labeling of antineoplastic and supportive medicines in China, Japan, and the US based on the WHO essential medicines list. [PDF]

Front Med (Lausanne)
Du C, Liu J, Wang C, Liu P.
europepmc   +1 more source

Serious Side Effects May Occur: The Painful Symptoms of Evolving Tort Liability [PDF]

, 2019
Rice, William H.T.
core   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Mass Spectrometry Proteomics: A Key to Faster Drug Discovery. [PDF]

J Med Chem
Tagliazucchi L, Costi MP.
europepmc   +1 more source

A Vascular Microphysiological Model of Lung Fibrosis Reveals That Myofibroblasts and IPF Patient‐Derived Fibroblasts Impair Angiogenesis and Vasculogenesis

Advanced Functional Materials, EarlyView.
A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria, Adriana Blazeski, Eunkyung Clare Ko, Tran Thai, Shania Dantes, David A. Barbie, Sarah E. Shelton, Roger D. Kamm   +7 more
wiley   +1 more source

Food Compass Score vs FDA Healthy Labeling and Consumer Purchases: A Randomized Clinical Trial.

JAMA Netw Open
Fan B, Fuller K, Sharib JR, Pomeranz JL, Wang M, Wang L, Mozaffarian D, Cash SB.   +7 more
europepmc   +1 more source

Assessing Readability and Usability of Electronic Medicine Package Leaflets in South Korea: A Mixed-Methods Study. [PDF]

Drug Healthc Patient Saf
Yang J, Kwon K.
europepmc   +1 more source

Tailoring the Properties of Functional Materials With N‐Oxides

Advanced Functional Materials, EarlyView.
The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich, Michelle Kobus, Shirin Mesgarha, Erica Moretto, Laurens Grosche, Wolfgang Maison   +5 more
wiley   +1 more source

Enhancing Severe Neutropenia Prediction: PKPD-Informed Labeling for Machine Learning Models Trained on Real-World Data. [PDF]

Clin Pharmacol Ther
O'Hanlon CJ, Denck J, Ozkirimli E, Bendels S, Jamois C, Chavanne C, Fey D, Porkka K, Brück O, Wang K.   +9 more
europepmc   +1 more source

Incentivizing Postmarketing Pharmaceutical Product Safety Testing with Extension of Exclusivity Periods [PDF]

, 2008
Kushner, Leslie
core   +1 more source