Results 121 to 130 of about 1,838,559 (243)

Emotion Regulation Difficulties in Autism‐PTSD Co‐Occurrence

open access: yesAutism Research, EarlyView.
ABSTRACT Autistic individuals face an increased risk of experiencing traumatic events and of being significantly affected by them, whether these events are life‐threatening or social in nature. Emotion regulation (ER) difficulties are central to both conditions, yet their role in this neuropsychiatric co‐occurrence remains under‐researched.
Eldar Fayena   +6 more
wiley   +1 more source

Possible Signals of Ocular Disorders Associated with Gabapentinoids: A Three-Arm Study

open access: yesPharmaceuticals
Background: Gabapentinoids (gabapentin and pregabalin) are medications used to treat epilepsy and diabetic neuropathy. Reports of gabapentinoid-associated adverse drug reactions (ADRs) are increasing.
Mya Murray   +6 more
doaj   +1 more source

Psychosocial interventions in drug misuse: a framework and toolkit for implementing NICE-recommended treatment interventions. [PDF]

open access: yes, 2010
Psychosocial Interventions for Drug Misuse was commissioned by the National Treatment Agency for Substance Misuse (NTA) from the British Psychological Society (BPS) to provide support for drug treatment providers and commissioners wishing to develop or ...
Mitcheson, Luke   +2 more
core  

Metabolic fate of drugs of abuse and new psychoactive substances: A pilot study on a novel workflow using a zebrafish embryo model combined with human microdosing

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study was to develop a novel workflow to identify human urine biomarkers for drugs of abuse and new psychoactive substances. Metabolites of amphetamine, cocaine, LSD, MDMA, methamphetamine, THC, MDMB‐CHMICA, and MDPPP were first identified in a zebrafish embryo (ZE) metabolism study followed by comparison to most abundant human ...
Simon K. Wellenberg   +7 more
wiley   +1 more source

Normalizing the Deviant?: Arrestees and the Normalization of Drug Use [PDF]

open access: yes, 2004
Traditionally in the UK scant research attention has been paid to the arrestee population. The introduction of the NEW-ADAM programme has done much to change this.
Patton, DJ
core   +1 more source

Trajectories, Transitions and Turning Points: Sports, Substance Misuse and Desistance. [PDF]

open access: yes, 2012
Despite well-established health benefits of physical exercise (Department of Health 2004; 2010; Pang et al., 2008), sport has played relatively little part in adult alcohol and drug treatment programmes.
Landale, Sarah A, LANDALE, SARAH,A
core  

A scoping review of thresholds for responder and time‐to‐event analysis of patient‐reported outcomes in breast cancer trials

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Patient‐reported outcomes (PROs) are essential for assessing clinical benefit and tolerability from the patient's perspective. In oncology trials, PRO data analysis often involves responder and time‐to‐event analyses, which depend on predefined thresholds to determine clinically meaningful change.
Anna Margarete Maria Thurner   +5 more
wiley   +1 more source

Zuranolone: A case study in (regulatory) rush to judgement?

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove   +4 more
wiley   +1 more source

The role of positive parental involvement in preventing drug and substance misuse among young people in Zimbabwe: a qualitative study

open access: yesBMJ Open
Objectives Our study explores the potential of positive parental involvement in preventing drug and substance misuse among young people in Zimbabwe.Design We adopted a qualitative approach to explore the role of positive parental involvement in ...
Itai Kabonga   +3 more
doaj   +1 more source

Safety concerns reported by coroners following fentanyl patch fatalities in England, Wales and Northern Ireland between 1997 and 2024

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim To identify safety concerns reported by coroners following fentanyl patch‐related deaths in England, Wales and Northern Ireland, and determine differences in coronial reporting. Methods A systematic case series linking the National Programme on Substance Use Mortality (NPSUM) and the Preventable Deaths Tracker (PDT) (https ...
Eman Mshari   +2 more
wiley   +1 more source

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