Results 121 to 130 of about 86,096 (311)

Early-onset prescription drug misuse in Indiana youth. [PDF]

Addict Behav, 2023
Parker MA, Zapolski TC, Carson I, Waldron MC.   +3 more
europepmc   +1 more source

Using non‐linear slide decks to administer individualized problem‐based learning assessments within pharmacology education

British Journal of Clinical Pharmacology, EarlyView.
Aim Problem‐based learning (PBL) is an established approach in medical, nursing, pharmacy and veterinary medicine education. This study describes the implementation and aims to evaluate the use of non‐linear slide decks as a method to deliver PBL as individualized student assessments within pharmacology education. This approach, originally developed in
Wendy R. Francis, Nia A. Davies, Aidan Seeley   +2 more
wiley   +1 more source

Prisons and Drugs: A global review of incarceration, drug use and drug services. Report 12 [PDF]

, 2007
Prisons play an important role in drug policy. They are used to punish people who break drug laws and they also hold a large number of people who have experience of drug use and drug problems.
Brentari, C., Stevens, Alex, Khoei, E.M., Dolan, K.   +3 more
core  

A scoping review of thresholds for responder and time‐to‐event analysis of patient‐reported outcomes in breast cancer trials

British Journal of Clinical Pharmacology, EarlyView.
Patient‐reported outcomes (PROs) are essential for assessing clinical benefit and tolerability from the patient's perspective. In oncology trials, PRO data analysis often involves responder and time‐to‐event analyses, which depend on predefined thresholds to determine clinically meaningful change.
Anna Margarete Maria Thurner, Daniela Krepper, Micha Johannes Pilz, Lisa Marie Storz, Maike Thumfart, Johannes Maria Giesinger   +5 more
wiley   +1 more source

The role of positive parental involvement in preventing drug and substance misuse among young people in Zimbabwe: a qualitative study

BMJ Open
Objectives Our study explores the potential of positive parental involvement in preventing drug and substance misuse among young people in Zimbabwe.Design We adopted a qualitative approach to explore the role of positive parental involvement in ...
Itai Kabonga, Courage Kusemwa, Irony Mazuruse, Enock Musara   +3 more
doaj   +1 more source

Zuranolone: A case study in (regulatory) rush to judgement?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove, Milutin Kostic, Barbara Mintzes, Gianna D'Ambrozio, Allen Shaughnessy   +4 more
wiley   +1 more source

Exploring the Potential Impact of GLP-1 Receptor Agonists on Substance Use, Compulsive Behavior, and Libido: Insights from Social Media Using a Mixed-Methods Approach

Brain Sciences
Glucagon-like peptide-1 (GLP-1) is involved in a range of central and peripheral pathways related to appetitive behavior. Hence, this study explored the effects of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) on substance and behavioral ...
Davide Arillotta, Giuseppe Floresta, G. Duccio Papanti Pelletier, Amira Guirguis, John Martin Corkery, Giovanni Martinotti, Fabrizio Schifano   +6 more
doaj   +1 more source

Cigarette and e-cigarette use trajectories and prospective prescription psychotherapeutic drug misuse among adolescents and young adults. [PDF]

Addict Behav, 2023
Harton MR, Seo DC, Evans-Polce RJ, Nguyen I, Parker MA.   +4 more
europepmc   +1 more source

Effect of carbamazepine on the pharmacokinetics of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader, in healthy adults

British Journal of Clinical Pharmacology, EarlyView.
Aim To evaluate the effects of carbamazepine, a strong cytochrome P450 (CYP)3A4 inducer, on the pharmacokinetics and safety of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader. Methods This was a phase 1, open‐label, fixed‐sequence, two‐period study in healthy adult participants.
Hechuan Wang, Jennifer A. Winton, Kyle T. Matschke, Alexandre Stouffs, Kimberly C. Lee, Yuanyuan Zhang, Wenlian Qiao, Weiwei Tan   +7 more
wiley   +1 more source

The development of a patient-reported outcome measuring opioid use disorder financial toxicity: Establishing content validity and reliability

Drug and Alcohol Dependence Reports
Background: Financial barriers are a major obstacle to engagement in medication treatment for opioid use disorder (OUD), contributing to poor adherence, reduced quality of life, and psychological distress.
Precious Anyanwu, Tyler J. Varisco, Olajumoke A. Olateju, Lauren R. Gilbert, Motolani E. Ogunsanya, E. James Essien, Michael L. Johnson, Vaishnavi Tata, J. Douglas Thornton   +8 more
doaj   +1 more source