Results 121 to 130 of about 873,917 (301)

Patterns and trends of drug abuse in Summit and Stark Counties, Ohio : a report prepared for the Ohio Substance Abuse Monitoring (OSAM) Network

open access: yes
Semiannual; Electronic coverage as of Sept. 26, 2006: June 1999/Jan. 2000-; Description based on: June 1999/Jan. 2000 issue; title from cover of PDF (viewed Sept.
Ohio Substance Abuse Monitoring Network.
core  

Perspectives on drugs: Drug consumption rooms: an overview of provision and evidence.

open access: yes, 2016
Supervised drug consumption facilities, where illicit drugs can be used under the supervision of trained staff, have been operating in Europe for the last three decades.

core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Brief strategic family therapy for adolescent drug abuse.

open access: yes, 2003
To ensure that treatment providers apply the most current scientifically supported approaches to their patients, NIDA has supported the development of the "Therapy Manuals for Drug Addiction" series.

core  

Drug testing in Europe: monitoring results of the Trans European Drug Information (TEDI) project.

open access: yes, 2015
Drug testing is a harm reduction strategy that has been adopted by certain countries in Europe. Drug users are able to hand in their drugs voluntarily for chemical analysis of composition and dose.
Ventura Vilamala, Mireia   +6 more
core   +1 more source

Determination of resorcinol, ferulic acid, phenylethylresorcinol and benzoyl peroxide in freckle whitening cosmetics by high performance liquid chromatography

open access: yesShanghai yufang yixue
ObjectiveTo establish an analytical method for the determination of resorcinol, ferulic acid, phenethylresorcinol and benzoyl peroxide in freckle whitening cosmetics by high performance liquid chromatography (HPLC), to provide data support for the ...
YANG Ruoxuan   +5 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Serum Concentrations of Antidepressant Drugs in a Naturalistic Setting : Compilation Based on a Large Therapeutic Drug Monitoring Database

open access: yes, 2009
A compilation of therapeutic drug monitoring data for 15 antidepressant drugs in a naturalistic routine clinical setting is presented. A substantial number of serum concentrations, at different daily doses, are outlined, and the intraindividual and ...
Reis, Margareta,   +3 more
core  

Towards Strengthened Preparedness and Response to New Psychoactive Substances in Europe

open access: yesEmerging Trends in Drugs, Addictions, and Health
In January 2022, the European Commission proposed to strengthen the mandate of the EMCDDA, transforming it into the new EU Drugs Agency (EUDA) [1]. This new regulation aims to improve data sharing, preparedness, surveillance, risk assessment, early ...
A. Gallegos
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

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