Results 1 to 10 of about 22,157,959 (291)

The interaction between aging and protein malnutrition modulates peritoneal macrophage function: An experimental study in male mice

Experimental Gerontology, 2023
Malnutrition is considered one of the most common problems in the elderly population worldwide and can significantly interfere in health evolution in these individuals, predisposing them to increased infection susceptibility.
Gabriela Kodja Vivian, Renaira Oliveira da Silva, Andressa Cristina Antunes Santos, Araceli Aparecida Hastreiter, Carolina Carvalho Dias, Edson Naoto Makiyama, Primavera Borelli, Claudia de Oliveira Rodrigues, Ricardo Ambrósio Fock   +8 more
doaj   +1 more source

VLP-Based Vaccines as a Suitable Technology to Target Trypanosomatid Diseases

Vaccines, 2021
Research on vaccines against trypanosomatids, a family of protozoa that cause neglected tropical diseases, such as Chagas disease, leishmaniasis, and sleeping sickness, is a current need.
Aline Maria Vasconcelos Queiroz, Johny Wysllas de Freitas Oliveira, Cláudia Jassica Moreno, Diego M. A. Guérin, Marcelo Sousa Silva   +4 more
doaj   +1 more source

The Knockout for G Protein-Coupled Receptor-Like PfSR25 Increases the Susceptibility of Malaria Parasites to the Antimalarials Lumefantrine and Piperaquine but Not to Medicine for Malaria Venture Compounds

Frontiers in Microbiology, 2021
Previously we have reported that the G protein-coupled receptor (GPCR)-like PfSR25 in Plasmodium falciparum is a potassium (K+) sensor linked to intracellular calcium signaling and that knockout parasites (PfSR25-) are more susceptible to oxidative ...
Benedito M. Santos, Bárbara K. M. Dias, Myna Nakabashi, Celia R. S. Garcia   +3 more
doaj   +1 more source

Association between APOA1 gene (rs670) single-nucleotide polymorphism and dyslipidaemia: a systematic review and meta-analysis [PDF]

Exploration of Endocrine and Metabolic Diseases
Background: Metabolic syndrome and dyslipidaemia increase the risk of death by two or three times. In this context, the role of apolipoprotein A-I (Apo A-I), the main structural protein of high-density lipoprotein (HDL), stands out, since its anti ...
Cauan Farias Ananias, Mateus Oliveira Fernandes, Antônia Gabriella de Souza Freitas, Sarah Maria Guilherme Oliveira, Lais Maurício Kfuri, Emanuel Paula Magalhães, Glautemberg de Almeida Viana, Bruna Ribeiro Duque, Izabell Maria Martins Teixeira, Natasha Maria Lima Pinheiro, Mac Dionys Rodrigues da Costa, Ramon Róseo Paula Pessoa Bezerra de Menezes, Tiago Lima Sampaio   +12 more
doaj   +1 more source

Modulatory Effect of Lippia alba Essential Oil on the Activity of Clinically Used Antimicrobial Agents on Salmonella typhi and Shigella dysenteriae Biofilm

Scientia Pharmaceutica, 2018
The essential oil obtained from the leaves of Lippia alba (Mill.) N.E. Brown (Verbenaceae) has shown great pharmacological potential as an analgesic, antispasmodic, and antimicrobial agent.
Andressa Batista, Hilania Dodou, Matheus Rodrigues, Pedro Pereira, Gleilton Sales, Suelen Medeiros, Nádia Nogueira   +6 more
doaj   +1 more source

Acute Promyelocytic Leukemia (APL): A Review of the Classic and Emerging Target Therapies towards Molecular Heterogeneity

Future Pharmacology, 2023
The occurrence of severe bleeding syndrome because of the PML-RARα fusion protein is a life-threatening event in APL. This protein destabilizes homeostasis, maturation, remodeling, and tissue regeneration in addition to hampering the maintenance and ...
Tâmara Dauare de Almeida, Fernanda Cristina Gontijo Evangelista, Adriano de Paula Sabino   +2 more
doaj   +1 more source

A practice analysis of toxicology

Regulatory Toxicology and Pharmacology, 2016
In 2015, the American Board of Toxicology (ABT), with collaboration from the Society of Toxicology (SOT), in consultation with Professional Examination Service, performed a practice analysis study of the knowledge required for general toxicology.
Wood, Carol S., Weis, Christopher P., Caro, Carla M., Roe, Amy   +3 more
openaire   +2 more sources

Correction: de Almeida et al. Acute Promyelocytic Leukemia (APL): A Review of the Classic and Emerging Target Therapies towards Molecular Heterogeneity. Future Pharmacol. 2023, 3, 162–179

Future Pharmacology, 2023
In the original publication [...]
Tâmara Dauare de Almeida, Fernanda Cristina Gontijo Evangelista, Adriano de Paula Sabino   +2 more
doaj   +1 more source

Antimicrobial Effects of Violacein against Planktonic Cells and Biofilms of Staphylococcus aureus

Molecules, 2017
Violacein is an indole compound, produced by Chromobacterium violaceum, a bacteria present in tropical and subtropical areas. Among its numerous biological activities, its antimicrobial potential stands out. This study aims to determine the antimicrobial
Andressa H. M. Batista, Anne C. D. Moreira, Rafael M. de Carvalho, Gleilton W. P. Sales, Patrícia C. N. Nogueira, Thalles B. Grangeiro, Suelen C. Medeiros, Edilberto R. Silveira, Nádia A. P. Nogueira   +8 more
doaj   +1 more source

Computational approach towards the design of artemisinin–thymoquinone hybrids against main protease of SARS-COV-2

Future Journal of Pharmaceutical Sciences, 2021
Background The sanitary emergency installed in the world, generated by the pandemic of COVID-19, instigates the search for scientific strategies to mitigate the damage caused by the disease to different sectors of society.
Victor Moreira de Oliveira, Matheus Nunes da Rocha, Emanuel Paula Magalhães, Francisco Rogênio da Silva Mendes, Márcia Machado Marinho, Ramon Róseo Paula Pessoa Bezerra de Menezes, Tiago Lima Sampaio, Hélcio Silva dos Santos, Alice Maria Costa Martins, Emmanuel Silva Marinho   +9 more
doaj   +1 more source