Results 41 to 50 of about 22,157,959 (291)

Intestinal parasites and sexually transmitted infections in a socially vulnerable rural community in southern Bahia, Brazil

Journal of Infection in Developing Countries
Introduction: Intestinal parasites and sexually transmitted infections (STI) are frequent among people living in conditions of social vulnerability.
Nilo MPV Barreto, Marina MB Farias, Weslei AC Araújo, Joelma N de Souza, Cíntia de L Oliveira, Larissa M Sampaio, Alex B da S Souza, Noilson LS Gonçalves, Bernardo Galvão-Castro, Márcia CA Teixeira, Neci M Soares   +10 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

In Vitro Biological Evaluation of Titanium Implants Anodized With Aqueous Extract of Psidium guajava and Conventional Electrolytes

International Journal of Biomaterials
Titanium implants can release ions that damage cells. Anodization creates a protective oxide layer, but conventional acid methods raise environmental and safety concerns.
Felipe Gustavo Dias, Gabriela Zimmermann Prado Rodrigues, Isadora Schell Frozza, Carlos Henrique Amaro da Silva, Fernando Dal Pont Morisso, Cláudia Trindade Oliveira, Günther Gehlen, Ana Luiza Ziulkoski   +7 more
doaj   +1 more source

Toxicological analysis. Methodology, indication, and evaluation

, 2013
Clinical toxicological analysis can significantly contribute toward the confirmation or exclusion of poisoning, especially if clinical signs and symptoms of unknown origin have to be explained.
Desel, Herbert
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Organelle-specific crosstalk between calcium and redox signaling in pancreatic β-cells in physiology and type 2 diabetes

Frontiers in Network Physiology
Two of the main intracellular signaling molecules in pancreatic β-cells are calcium (Ca2+) and reactive oxygen species (ROS). Ca2+ signaling is essential for regulating energy metabolism, insulin secretion, and the modulation of key factors involved in β-
Lucas Rafael Pereira Camara, Eloisa Aparecida Vilas-Boas   +1 more
doaj   +1 more source

ICPP radiological and toxicological sabotage analysis [PDF]

, 1995
In June of 1993, the Department of Energy (DOE) issued Notice 5630.3A, {open_quotes}Protection of Departmental Facilities Against Radiological and Toxicological Sabotage,{close_quotes} which states that all significant radiological and toxicological ...
Mortensen, F.G., Kubiak, V.R.
core  

Non‐Additive Criteria Assessment in Sustainability Evaluation of High Entropy Alloys: A Toxicity‐Weighted Framework

Advanced Engineering Materials, EarlyView.
Sustainability assessment requires methodologies that appropriately distinguish between additive and non‐additive material properties. A toxicity‐weighted scoring system is developed and applied that accounts for the disproportionate influence of highly toxic constituents through nonlinear weighting functions, providing more realistic estimates than ...
Seth Mehalic, Oladele A. Ogunseitan, Julie M. Schoenung   +2 more
wiley   +1 more source

Unravelling the mode of action of the Tres Cantos Antimalarial Set (TCAMS): investigating the mechanism of potent antimalarial compounds potentially targeting the human serotonin receptor

Malaria Journal
Background Despite the strides made in recent decades, the resistance observed in existing antimalarial drugs, and the intricate life cycle of the Plasmodium parasite underscore the pressing need to develop novel and effective therapeutic interventions ...
Benedito Matheus dos Santos, Lenna Rosanie Cordero Mallaupoma, Mateus Fila Pecenin, Abhinab Mohanty, Angela Lu, Paula J. Bartlett, Andrew P. Thomas, Francisco-Javier Gamo, Celia R. S. Garcia   +8 more
doaj   +1 more source

Prevalence and antimicrobial susceptibility of respiratory pathogens in patients with cystic fibrosis

Brazilian Journal of Infectious Diseases, 2010
Respiratory infection is very common in patients suffering from cystic fibrosis (CF). However, the antimicrobial resistance rate of isolates from CF patients is not often documented.
Vilma Almeida Paixão, Tânia Fraga Barros, Clélia Maria C. Mota, Tamy Fagundes Moreira, Maria Angélica Santana, Joice Neves Reis   +5 more
doaj   +1 more source