Results 11 to 20 of about 22,157,959 (291)

Piplartine-Inspired 3,4,5-Trimethoxycinnamates: Trypanocidal, Mechanism of Action, and In Silico Evaluation

Molecules, 2023
Chagas disease (CD) is one of the main neglected tropical diseases that promote relevant socioeconomic impacts in several countries. The therapeutic options for the treatment of CD are limited, and parasite resistance has been reported.
Carlos S. M. B. Filho, Ramon R. P. P. B. de Menezes, Emanuel P. Magalhães, Yunierkis P. Castillo, Alice M. C. Martins, Damião P. de Sousa   +5 more
doaj   +1 more source

An Exploratory Study of the Metabolite Profiling from Pesticides Exposed Workers

Metabolites, 2023
Pesticides constitute a category of chemical products intended specifically for the control and mitigation of pests. With their constant increase in use, the risk to human health and the environment has increased proportionally due to occupational and ...
Daniela Magalhães Nolasco, Michele P. R. Mendes, Luiz Paulo de Aguiar Marciano, Luiz Filipe Costa, Adriana Nori De Macedo, Isarita Martins Sakakibara, Alessandra Cristina Pupin Silvério, Maria José N. Paiva, Leiliane C. André   +8 more
doaj   +1 more source

Escherichia coli Bloodstream Infections in Patients at a University Hospital: Virulence Factors and Clinical Characteristics

Frontiers in Cellular and Infection Microbiology, 2019
Extraintestinal pathogenic Escherichia coli (ExPEC) isolates are responsible for many bloodstream infections. The aim of this study was to characterize E.
Ana Paula Daga, Vanessa Lumi Koga, João Gabriel Material Soncini, Caroline Martins de Matos, Marcia Regina Eches Perugini, Marsileni Pelisson, Renata Katsuko T. Kobayashi, Eliana Carolina Vespero   +7 more
doaj   +1 more source

Meta-analysis of aspirin for the prevention of preeclampsia: do the main randomized controlled trials support an association between low-dose aspirin and a reduced risk of developing preeclampsia? [PDF]

, 2006
Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM) Department of BiochemistrySão Paulo University of Pharmaceutical Sciences Clinical and Toxicological Analysis DepartmentSão Paulo University Institute of Mathematics and ...
Rudnicki, Martina [UNIFESP], Pereira, Tiago da Veiga [UNIFESP], Pereira, Tiago V., Soler, Júlia M. P. [UNIFESP], Soler, Júlia M. P., José E. Krieger, Júlia M. P. Soler, Krieger, José E., Martina Rudnicki, Rudnicki, Martina, Tiago V. Pereira, Krieger, Jose Eduardo   +11 more
core   +1 more source

Bisphosphonate-Based Molecules as Potential New Antiparasitic Drugs

Molecules, 2020
Neglected tropical diseases such as Chagas disease and leishmaniasis affect millions of people around the world. Both diseases affect various parts of the globe and drugs traditionally used in therapy against these diseases have limitations, especially ...
Joice Castelo Branco Santos, Jonathas Alves de Melo, Sweta Maheshwari, Wendy Marina Toscano Queiroz de Medeiros, Johny Wysllas de Freitas Oliveira, Cláudia Jassica Moreno, L. Mario Amzel, Sandra B. Gabelli, Marcelo Sousa Silva   +8 more
doaj   +1 more source

Genomic insights of high-risk clones of ESBL-producing Escherichia coli isolated from community infections and commercial meat in southern Brazil

Scientific Reports, 2022
During a microbiological and genomic surveillance study conducted to investigate the molecular epidemiology of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli from community-acquired urinary tract infections (UTI) and commercial meat ...
João Gabriel Material Soncini, Louise Cerdeira, Elder Sano, Vanessa Lumi Koga, Ariane Tiemy Tizura, Zuleica Naomi Tano, Gerson Nakazato, Renata Katsuko Takayama Kobayashi, Caio Augusto Martins Aires, Nilton Lincopan, Eliana Carolina Vespero   +10 more
doaj   +1 more source

Modulation of miR-26a-5p and miR-15b-5p Exosomal Expression Associated with Clopidogrel-Induced Hepatotoxicity in HepG2 Cells

Frontiers in Pharmacology, 2017
Clopidogrel is an essential antiplatelet drug used to prevent thrombosis complications associated with atherosclerosis. However, hepatotoxicity is a potential adverse effect related to clopidogrel therapy.
Renata C. Costa de Freitas, Raul H. Bortolin, Mariana B. Lopes, Letícia Tamborlin, Letícia Meneguello, Vivian N. Silbiger, Rosario D. C. Hirata, Mário H. Hirata, Augusto D. Luchessi, Augusto D. Luchessi, André D. Luchessi   +10 more
doaj   +1 more source

A comprehensive toxicological analysis of panel of unregulated e-cigarettes to human health [PDF]

Electronic cigarettes, commonly referred to as e-cigarettes have gained popularity over recent years especially among young individuals. In the light of the escalating prevalence of the use of these products and their potential for long-term health ...
Sivasubramaniam, S., Burn, L., Drake, S., Corcoran, M., Walkman, D., Kermanizadeh, A., Mierlea, S., Dowse, D., Guraka, A., Waldron, S., Shawa, T. S.   +10 more
core   +1 more source

Toxicological Analysis of Exhumed Specimens: A Challenge for Toxicologists [PDF]

, 2016
The objective of this work is to describe the type of biological samples submitted for toxicological analysis after exhumation. Forensic toxicologists receive a variety of biological samples, but exhumed biological specimens with varying degrees of ...
Muhammad Taimoor Chaudhary, Wattoo, Sardar Ali, Ashiq, Muhammad Zar, Mohammad Sarwar, Chaudhary, Muhammad Taimoor, Saima Afzal, Afzal, Saima, Sarwar, Mohammad, Mohammad Ashraf Tahir, Sardar Ali Wattoo, Tahir, Mohammad Ashraf, Muhammad Zar Ashiq   +11 more
core   +1 more source

A Systematic Review to Compare Chemical Hazard Predictions of the Zebrafish Embryotoxicity Test With Mammalian Prenatal Developmental Toxicity

, 2021
Originally developed to inform the acute toxicity of chemicals on fish, the zebrafish embryotoxicity test (ZET) has also been proposed for assessing the prenatal developmental toxicity of chemicals, potentially replacing mammalian studies.
AKGÜN ÖLMEZ, SEVCAN GÜL
core   +1 more source