Abstract Background and aims In 2020, British Columbia (BC), Canada, introduced ‘Prescribed Alternatives’ (PA) as an approach to offering regulated substances to people accessing the unregulated supply. This study aimed to estimate and compare prescribing characteristics of dextroamphetamine and methylphenidate stimulant PAs in BC, to estimate ...
Bin Zhao +11 more
wiley +1 more source
Acceptability and usability of a respiratory biosensor for drug overdose detection and first responder notification: a qualitative evaluation of perspectives from people who use drugs and wider stakeholders. [PDF]
Hnízdilová K +7 more
europepmc +1 more source
Clinicians' and people who use drugs' perspectives on artificial intelligence in addiction medicine
Abstract Background and aims Artificial intelligence (AI) may improve addiction medicine workflows and health outcomes but raises questions about data privacy and unintended harms for people who use drugs (PWUD). This qualitative study aimed to understand the perspectives of clinicians and PWUD regarding perceived benefits and concerns about clinical ...
Patrick J. A. Kelly +6 more
wiley +1 more source
A framework to determine naloxone saturation with simulation modeling and cost‐effectiveness methods
Abstract Background and aims Jurisdictions lack practical tools to determine data‐informed naloxone saturation targets that account for local overdose dynamics and resource constraints. We aimed to introduce a generalizable framework that integrates simulation modeling with cost‐effectiveness principles to identify local naloxone saturation targets ...
Zongbo Li +7 more
wiley +1 more source
Drugs Most Frequently Involved in Drug Overdose Deaths: United States, 2017-2023.
Garnett MF, Cisewski JA, Ahmad FB.
europepmc +1 more source
Abstract Background and aims People with substance use disorders have reduced life‐expectancy; however, risks of premature death from injuries and natural causes following an accidental overdose are not well characterised. This study aimed to estimate risk of premature death (by cause and over time), and disease burden following hospitalised accidental
Firouzeh Noghrehchi +5 more
wiley +1 more source
Youth and Young Adult National Overdose Rates: A Descriptive, Ecological Cross-Sectional Time-Trend Analysis of Drug Overdose Mortality in 10-24-Year-Olds in the United States. [PDF]
Wakefield J +4 more
europepmc +1 more source
Abstract Background and aims Cannabis edible products are increasingly being sold on the illicit market around the world. Use of these products, typically labelled as containing Δ‐9‐tetrahydrocannabinol (THC), has been linked to adverse health effects, particularly amongst adolescents.
Matthew Gardner +9 more
wiley +1 more source
Demographic characteristics and repeat overdose risk factors in 601 patients with intentional drug overdose in the emergency department: a cross-sectional study. [PDF]
Rong S +6 more
europepmc +1 more source
Abstract Aims To determine: (1) Population rates of fatal methylenedioxymethamphetamine (MDMA)‐related poisoning over the period 2016–2023, years with high closure rates in the National Coronial Information System (NDIS); (2) the case characteristics of known cases of fatal MDMA‐related poisoning, 2016–2025; and (3) whether there have been changes in ...
Shane Darke +5 more
wiley +1 more source

