Results 191 to 200 of about 1,984,102 (295)

Prescribed alternative stimulants among people who use unregulated stimulants: Examining the association between maximum dose reached and medication discontinuation in the first 3 years of implementation in British Columbia, Canada

open access: yesAddiction, EarlyView.
Abstract Background and aims In 2020, British Columbia (BC), Canada, introduced ‘Prescribed Alternatives’ (PA) as an approach to offering regulated substances to people accessing the unregulated supply. This study aimed to estimate and compare prescribing characteristics of dextroamphetamine and methylphenidate stimulant PAs in BC, to estimate ...
Bin Zhao   +11 more
wiley   +1 more source

Clinicians' and people who use drugs' perspectives on artificial intelligence in addiction medicine

open access: yesAddiction, EarlyView.
Abstract Background and aims Artificial intelligence (AI) may improve addiction medicine workflows and health outcomes but raises questions about data privacy and unintended harms for people who use drugs (PWUD). This qualitative study aimed to understand the perspectives of clinicians and PWUD regarding perceived benefits and concerns about clinical ...
Patrick J. A. Kelly   +6 more
wiley   +1 more source

A framework to determine naloxone saturation with simulation modeling and cost‐effectiveness methods

open access: yesAddiction, EarlyView.
Abstract Background and aims Jurisdictions lack practical tools to determine data‐informed naloxone saturation targets that account for local overdose dynamics and resource constraints. We aimed to introduce a generalizable framework that integrates simulation modeling with cost‐effectiveness principles to identify local naloxone saturation targets ...
Zongbo Li   +7 more
wiley   +1 more source

Accidental overdose admissions and premature death: A large population‐based data‐linkage cohort study in New South Wales, Australia (PAVLOVA 4)

open access: yesAddiction, EarlyView.
Abstract Background and aims People with substance use disorders have reduced life‐expectancy; however, risks of premature death from injuries and natural causes following an accidental overdose are not well characterised. This study aimed to estimate risk of premature death (by cause and over time), and disease burden following hospitalised accidental
Firouzeh Noghrehchi   +5 more
wiley   +1 more source

Identification and quantification of Δ‐9‐tetrahydrocannabinol and the synthetic cannabinoid MDMB‐4en‐PINACA in edible products seized by United Kingdom police in 2024

open access: yesAddiction, EarlyView.
Abstract Background and aims Cannabis edible products are increasingly being sold on the illicit market around the world. Use of these products, typically labelled as containing Δ‐9‐tetrahydrocannabinol (THC), has been linked to adverse health effects, particularly amongst adolescents.
Matthew Gardner   +9 more
wiley   +1 more source

Methylenedioxymethamphetamine (MDMA)‐related fatal poisoning in Australia, 2016 to 2025: Trends, characteristics and toxicology

open access: yesAddiction, EarlyView.
Abstract Aims To determine: (1) Population rates of fatal methylenedioxymethamphetamine (MDMA)‐related poisoning over the period 2016–2023, years with high closure rates in the National Coronial Information System (NDIS); (2) the case characteristics of known cases of fatal MDMA‐related poisoning, 2016–2025; and (3) whether there have been changes in ...
Shane Darke   +5 more
wiley   +1 more source

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